Results 71 to 80 of about 2,659,137 (363)

Pearl Millet Forage Water Use Efficiency

open access: yesAgronomy, 2020
Pearl millet (Pennisitum glaucum L.) is a warm season C4 grass well adapted to semiarid climates where concerns over scarce and depleting water resources continually prompt the search for water efficient crop management to improve water use efficiency ...
Bradley Crookston   +3 more
doaj   +1 more source

Equity-Efficiency Optimizing Resource Allocation: The Role of Time Preferences in a Repeated Irrigation Game [PDF]

open access: yes, 2014
We study repeated water allocation decisions among small scale irrigation users in Tanzania. In a treatment replicating water scarcity conditions, convexities in production make that substantial efficiency gains can be obtained by deviating from equal ...
Besley T.   +6 more
core   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Potentials of hydrogels in rainfed soil to conserve soil moisture and fertility to maximize the wheat yield

open access: yesSoil & Environment, 2020
The availability of limited irrigation water in rainfed regions is the most challenging constraint to harvest the maximum agronomic benefits. The adaptation of smart water-saving techniques is desperate to combat soil moisture stress and soil quality ...
Aftab Ahmad Shaikh   +9 more
doaj   +1 more source

Technical Change Performance and Water Use Efficiency in the Irrigated Areas: Data Envelopment Analysis Approach [PDF]

open access: yes
In order to cope with the water scarcity, Tunisia has to manage efficiently the water demand of the economic and social sectors mainly that of the agricultural irrigated activities.
Chemak, Fraj
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

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