Results 41 to 50 of about 45,804 (264)
WATER VAPOR TRANSPORT IN PLASTERS CONTAINING SUPERABSORBENT POLYMERS
Proceedings of International Structural Engineering and Construction, 2020 A proper characterization of material properties represents an important step towards an efficient building design. Considering the present issues in the construction sector, moisture loads pose a risk not only to increased material deterioration but also to the health of building inhabitants.
Jan Fořt +3 more
openaire +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Gaoyuan qixiang, 2022 By using the ECMWF Re-Analyses version5 data， the water vapor transport type over the Yarlung Zangbo Grand Canyon area of southeastern Qinghai-Xizang Plateau（QXP）are categorized， the daily variation characteristics of land-atmospheric water heat exchange
Qiang ZHANG +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
Journal of Hydrology: Regional StudiesStudy region: Ili River Valley, China: Study focus: The spatial and temporal variations of water vapor content and precipitation conversion efficiency in the Ili River Valley from 1979 to 2022 are quantified using the reanalysis dataset, and the water ...
Na Guo +5 more
doaj +1 more source
Frontiers in Earth Science, 2020 Water vapor transport has been highlighted as a critical process in Arctic snowpacks, shaping the snow cover structure in terms of density, thermal conductivity, and temperature profile among others.
Mahdi Jafari +14 more
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source