Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Fossil Carbon Release and Exports from Subsurface Sedimentary Bedrock Weathering in Mountainous Watersheds [PDF]
Jiamin Wan +11 more
openalex +1 more source
The Economics of Water Resource Allocation: Valuation Methods and Policy Implications [PDF]
In this chapter a ‘watershed economics approach’ that could be applied in Cyprus is proposed which is composed of two important stages. In Stage I economic valuation techniques are used to establish the economic value of the competing demands for surface
Groom, Ben, Koundouri, Phoebe
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Water quality issues in the Illinois River watershed: A proposal for new voluntary incentives [PDF]
Concerns about water quality degradation exist in Northwest Arkansas. The purpose of this study was to analyze the potential usefulness of U.S. conservation programs in addressing water quality concerns on farms in the Illinois River watershed as well as
Hodges, Tory B., Popp, Jennie S.
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Dynamic modeling of nitrogen losses in river networks unravels the coupled effects of hydrological and biogeochemical processes [PDF]
The importance of lotic systems as sinks for nitrogen inputs is well recognized. A fraction of nitrogen in streamflow is removed to the atmosphere via denitrification with the remainder exported in streamflow as nitrogen loads.
Alexander, Richard B. +9 more
core +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
This article aims at understanding the qualification of natural resources as an endogenous and iterative normative process involving actors with different interests, often conflicting.
Arnaud Buchs
doaj +1 more source
Adult Trichoptera of the Devil Track River Watershed, Cook County, Minnesota and Their Role in Biomonitoring. [PDF]
Thirty two light trap collections of 7,797 adult Trichoptera made from 1990-1992, show that the Devil Track River Watershed in northeast Minnesota includes at least 16 families, 41 genera, and 101 species of caddisflies including three new state records:
MacLean, David B
core +3 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source

