Results 91 to 100 of about 236,702 (302)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Across the Watershed, Fall 2008

open access: yes, 2008
This is the quarterly publication of the Great Swamp Watershed Association (GSWA), a nonprofit watershed association working to protect the ecological, historic, and cultural integrity of the Great Swamp and its watershed.

core   +2 more sources

Processus de qualification et construction d’un compromis institutionnel territorialisé. La gestion intégrée de l’eau par bassin dans le canton de Fribourg (Suisse)

open access: yesDéveloppement Durable et Territoires, 2016
This article aims at understanding the qualification of natural resources as an endogenous and iterative normative process involving actors with different interests, often conflicting.
Arnaud Buchs
doaj   +1 more source

Transfers of Water from Watershed to Watershed

open access: yesGeografie, 1967
The increased water demand in certain localities requires in many instances the transfer of water from one watershed to another one. According to the National Water Management Plan, the territory of Czechoslovakia is divided into 35 main watersheds. More than 50 transfers between them have already been realised and another 35 are now being designed and
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Across the Watershed, Winter 2008

open access: yes, 2008
This is the quarterly publication of the Great Swamp Watershed Association (GSWA), a nonprofit watershed association working to protect the ecological, historic, and cultural integrity of the Great Swamp and its watershed.

core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Across the Watershed, Spring 2006

open access: yes, 2006
This is the quarterly publication of the Great Swamp Watershed Association (GSWA), a nonprofit watershed association working to protect the ecological, historic, and cultural integrity of the Great Swamp and its watershed.

core   +1 more source

Analisis Potensi Bencana Banjir Hilir Daerah Aliran Sungai Way Kuripan Kota Bandar Lampung

open access: yesRekayasa Sipil, 2019
The Way Kuripan River is one of the rivers in Bandar Lampung which overflows during the rainy season. Downstream of the river passes through several subdistrict, is Pesawahan, and Kota Karang.
Ayudia Hardiyani Kiranaratri   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy