Results 121 to 130 of about 562,443 (296)

Spatial characteristics of thunderstorm rainfall fields and their relation to runoff [PDF]

, 2003
The main aim of this study was to assess the ability of simple geometric measures of thunderstorm rainfall in explaining the runoff response from the watershed. For calculation of storm geometric properties (e.g.
Goodrich, DC, Myers, DE, Sorooshian, S, Syed, KH   +3 more
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Soil Erosion Modeling Using the Revised Universal Soil Loss Equation and a Geographic Information System in a Watershed in the Northeastern Brazilian Cerrado

Geosciences
Soils have an important task in maintaining vegetation cover and natural resources on Earth and are indispensable to societies. However, the accelerated soil erosion has become an environmental problem related to land settlement for agricultural ...
Wellynne Carla de Sousa Barbosa, Antonio José Teixeira Guerra, Gustavo Souza Valladares   +2 more
doaj   +1 more source

The nature of small-scale farmer managed irrigation systems in North West Province, Sri Lanka and potential for aquaculture [PDF]

, 2000
RRAs were carried out in two Small Tank Cascade systems (STCs) of North West Province, Sri Lanka (less than 1000 ha total watershed area). A total of 21 tanks and 7 villages were investigated with primary emphasis on two upper watershed communities.
Little, D.C., Murray, F.J.
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Spatial Correlations between Nitrogen Budgets and Surface Water and Groundwater Quality in Watersheds with Varied Land Covers

Agriculture
Anthropogenic nitrogen (N) inputs can have detrimental environmental effects, necessitating a comprehensive understanding of the nitrogen budget (NB) and its spatial correlation with the water quality.
Deok-Woo Kim, Eu Gene Chung, Eun Hye Na, Youngseok Kim   +3 more
doaj   +1 more source

Payment for Watershed Services: Opportunities and Realities [PDF]

, 2007
Many nations have found that regulatory approaches to land and water management have a limited impact. An alternative is to create incentives for sound management - under mechanisms known as payments for ecosystem services.
Ivan Bond
core  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Evaluation of Soil Hydraulic Properties in Northern and Central Tunisian Soils for Improvement of Hydrological Modelling

Land
The hydrological cycle is strongly affected by climate changes causing extreme weather events with long drought periods and heavy rainfall events. To predict the hydrological functioning of Tunisian catchments, modelling is an essential tool to estimate ...
Asma Hmaied, Pascal Podwojewski, Ines Gharnouki, Hanene Chaabane, Claude Hammecker   +4 more
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source