Results 131 to 140 of about 486,785 (279)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Evaluation of Soil Hydraulic Properties in Northern and Central Tunisian Soils for Improvement of Hydrological Modelling

open access: yesLand
The hydrological cycle is strongly affected by climate changes causing extreme weather events with long drought periods and heavy rainfall events. To predict the hydrological functioning of Tunisian catchments, modelling is an essential tool to estimate ...
Asma Hmaied   +4 more
doaj   +1 more source

Socio-economic and Environmental Perspectives of Sustainable Watershed Eco-System in Union Territory of Pondicherry [PDF]

open access: yes
The study conducted in the Karaikal region of the Union Territory of Pondicherry during 2004-05 has made a comparison of watershed and conventional systems.
Mahesh, N., Nasurudeen, P.
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

All that Glitters: A Review of Payments for Watershed Services in Developing Countries [PDF]

open access: yes, 2008
This report reviews the current status of payments for watershed services in developing countries. It highlights the main trends in the evolution of these schemes, synthesising the available evidence on their environmental and social impacts, and drawing
Ina T. Porras   +2 more
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Soil preferential flow dynamics in the southern drylands of India—a watershed based approach

open access: yesFrontiers in Water
Preferential flow refers to the specific pathways through which water flows, including biopores, fractures, and macropores. Soil preferential flow has become increasingly important in the face of changing climates, erratic rainfall patterns, and for ...
Pushpanjali   +11 more
doaj   +1 more source

Spatial characteristics of thunderstorm rainfall fields and their relation to runoff [PDF]

open access: yes, 2003
The main aim of this study was to assess the ability of simple geometric measures of thunderstorm rainfall in explaining the runoff response from the watershed. For calculation of storm geometric properties (e.g.
Goodrich, DC   +3 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Optimal Provision and Finance of Ecosystem Services: the Case of Watershed Conservation and Groundwater Management [PDF]

open access: yes
Payments for ecosystem services should be informed by how both the providing-resource and the downstream resource are managed. We develop an integrated model that jointly optimizes conservation investment in a watershed that recharges a downstream ...
Christopher Wada, James Roumasset
core  

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