Results 51 to 60 of about 860,678 (269)

Aquaporin‐4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Narcolepsy type 1 (NT1) is caused by the loss of hypocretin‐1 leading to excessive daytime sleepiness and cataplexy. Additionally, disrupted nighttime sleep has become an increasingly recognized feature of NT1. As the glymphatic fluid movement has been linked to sleep architecture, we investigated cerebrospinal fluid (CSF) Aquaporin‐4 (AQP4 ...
Jonas Ranke, Petra Steinacker, Steffen Halbgebauer, Patrick Oeckl, Geert Mayer, Markus Otto   +5 more
wiley   +1 more source

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos, Marwa Al‐Dubai, Denise Walther, Dominic Borie, Jan D. Lünemann, Marc Pawlitzki, Sven G. Meuth, Solveig Henneicke, Stefan Vielhaber, Stefanie Schreiber   +9 more
wiley   +1 more source

Quantum error mitigation in quantum annealing

npj Quantum Information
Quantum error mitigation (QEM) presents a promising near-term approach to reducing errors when estimating expectation values in quantum computing. Here, we introduce QEM techniques tailored for quantum annealing, using zero-noise extrapolation (ZNE).
Jack Raymond, Mohammad H. Amin, Andrew D. King, Richard Harris, William Bernoudy, Andrew J. Berkley, Kelly Boothby, Anatoly Smirnov, Fabio Altomare, Michael Babcock, Catia Baron, Jake Connor, Martin H. Dehn, Colin Enderud, Emile Hoskinson, Shuiyuan Huang, Mark W. Johnson, Eric Ladizinsky, Trevor Lanting, Allison J. R. MacDonald, Gaelen Marsden, Reza Molavi, Travis Oh, Gabriel Poulin-Lamarre, Hugh Ramp, Chris Rich, Berta Trullas Clavera, Nicholas Tsai, Mark Volkmann, Jed D. Whittaker, Jason Yao, Niclas Heinsdorf, Nitin Kaushal, Alberto Nocera, Marcel Franz, Jacek Dziarmaga   +35 more
doaj   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

The Wave

HCA Healthcare Journal of Medicine
Description Working as a nurse is stressful. Two things that help me decompress are the beach and fused glasswork. Both of those items are represented in this piece. I hand-cut glass to represent a wave and then fused it together in a kiln at high temperatures. Waves wash away my stress.
openaire   +2 more sources

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

Pengaruh Kemampuan Berkomunikasi dan Penggunaan Kode Isyarat Internasional Terhadap Tingkat Keselamatan Pelayaran Kapal Di Pelabuhan

Wave, 2023
Kemampuan berkomunikasi dan penggunaan kode isyarat internasional merupakan kemampuan interaksi yang dimiliki oleh individu atau seseorang di atas kapal untuk dapat berinteraksi dan bersosialisasi dengan individu atau orang lain.
Siwi Woro Herningsih, Amirullah, Vidiana Anggeranika, Yohanna Nurika   +3 more
doaj  

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li, Dong‐Lin Liang, Li‐Ping Gao, Wei‐Wei Zhang, Wei Zhou, A. Ruhan, Bing Xu, Run‐Dong Cao, Kang Xiao, Cao Chen, Qi Shi, Xiao‐Ping Dong   +11 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Wave–Wave Interaction of Unstable Baroclinic Waves

Journal of the Atmospheric Sciences, 1987
Two slightly unstable baroclinic waves in the two-layer Phillips model are allowed to interact with each other as well as the mean flow. A theory for small dissipation rates is developed to examine the role of wave–wave interaction in the dynamics of vacillation and aperiodicity in unstable systems.
Pedlosky, Joseph, Polvani, Lorenzo M.
openaire   +3 more sources