Results 41 to 50 of about 24,156,865 (214)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Enhancing coronary Wave Intensity Analysis robustness by high order central finite differences

Artery Research, 2014
Background: Coronary Wave Intensity Analysis (cWIA) is a technique capable of separating the effects of proximal arterial haemodynamics from cardiac mechanics.
Simone Rivolo, Kaleab N. Asrress, Amedeo Chiribiri, Eva Sammut, Roman Wesolowski, Lars Ø. Bloch, Anne K. Grøndal, Jesper L. Hønge, Won Y. Kim, Michael Marber, Simon Redwood, Eike Nagel, Nicolas P. Smith, Jack Lee   +13 more
doaj   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Use of wave intensity analysis during peripheral revascularisation: Lessons from cases study

Artery Research, 2013
Background: Wave propagation in arteries can be characterized by the wave-intensity approach. This has particularly well been studied in healthy ascending aortas, carotid, brachial and coronary arteries.
Valérie Lacroix, Marie Willemet, Emilie Marchandise, Christophe Beauloye, Robert Verhelst   +4 more
doaj   +1 more source

Identification of ring current proton precipitation driven by scattering of electromagnetic ion cyclotron waves

Fundamental Research, 2023
Among the most intense emissions in the Earth's magnetosphere, electromagnetic ion cyclotron (EMIC) waves are regarded as a critical candidate contributing to the precipitation losses of ring current protons, which however lacks direct multi-point ...
Binbin Ni, Yang Zhang, Xudong Gu
doaj   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

2.2 RE-REFLECTION OF BACKWARD PROPAGATING WAVES LEADS TO AMPLIFICATION OF THE FORWARD PRESSURE WAVE IN WAVE SEPARATION ANALYSIS

Artery Research, 2015
Introduction: In wave separation analysis, the pressure wave is decomposed into a single forward and backward component, which actually compounds all forward and backward propagating waves.
Patrick Segers*, Liesbeth Taelman, Joris Degroote, Jan Vierendeels   +3 more
doaj   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

2.6 FEASIBILITY OF AORTIC WAVE INTENSITY ANALYSIS FROM SEQUENTIALLY ACQUIRED CARDIAC MRI AND NON-INVASIVE CENTRAL BLOOD PRESSURE

Artery Research, 2018
Background: Wave intensity analysis (WIA) in the aorta offers important clinical and mechanistic insights but is difficult non-invasively. We performed WIA by combining high temporal resolution cardiovascular magnetic resonance (CMR) flow velocity and ...
Anish Bhuva, Niro Nadarajan, Andrew D’Silva, Camilla Torlasco, Redha Boubertakh, Siana Jones, Paul Scully, Rachel Bastiaenen, Guy Lloyd, Sanjay Sharma, James Moon, Kim Parker, Charlotte Manisty, Alun Hughes   +13 more
doaj   +1 more source