Results 71 to 80 of about 229,628 (276)

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini, Alessia Casarini, Niccolò Biagioli, Laura Mirandola, Daniela Ballotta, Paul Summers, Simona Scolastico, Laura Madrassi, Maurilio Genovese, Marcella Malagoli, Gaetano Cantalupo, Giada Giovannini, Matteo Pugnaghi, Niccolò Orlandi, Laura Tassi, Valeria Cuccarini, Domenico Aquino, Elena Tartara, Fulvia Palesi, Giuseppe Didato, Paolo Vitali, the 3TLE Study Group, Roberta Di Giacomo, Fabio Doniselli, Federica Mazzi, Carlo Andrea Galimberti, Claudia A. M. Gandini Wheeler‐Kingshott, Stefano Meletti, Anna Elisabetta Vaudano   +28 more
wiley   +1 more source

Identification of ring current proton precipitation driven by scattering of electromagnetic ion cyclotron waves

Fundamental Research, 2023
Among the most intense emissions in the Earth's magnetosphere, electromagnetic ion cyclotron (EMIC) waves are regarded as a critical candidate contributing to the precipitation losses of ring current protons, which however lacks direct multi-point ...
Binbin Ni, Yang Zhang, Xudong Gu
doaj   +1 more source

Propagation and reflection of pulse waves in flexible tubes and relation to wall properties [PDF]

, 2011
This thesis was submitted for the degree of Docter of Philosophy and awarded by Brunel University.The wall properties of the arteries play an important role in cardiovascular function. Stiffness of large artery is predictive of cardiovascular events.
Li, Ye
core  

Hemodynamic effects of a dielectric elastomer augmented aorta on aortic wave intensity: An in-vivo study [PDF]

, 2023
Dielectric elastomer actuator augmented aorta (DEA) represents a novel approach with high potential for assisting a failing heart. The soft tubular device replaces a section of the aorta and increases its diameter when activated.
Walter, Armando, Francesco Clavica, Perriard, Yves, Clavica, Francesco, Civet, Yoan, Obrist, Dominik, Armando Walter, Jahren, Silje Ekroll, Yoan Civet, Martinez, Thomas, Silje Ekroll Jahren, Ferrari, Lorenzo, Lorenzo Ferrari, Dominik Obrist, Yves Perriard, Thomas Martinez   +15 more
core   +1 more source

2.2 RE-REFLECTION OF BACKWARD PROPAGATING WAVES LEADS TO AMPLIFICATION OF THE FORWARD PRESSURE WAVE IN WAVE SEPARATION ANALYSIS

Artery Research, 2015
Introduction: In wave separation analysis, the pressure wave is decomposed into a single forward and backward component, which actually compounds all forward and backward propagating waves.
Patrick Segers*, Liesbeth Taelman, Joris Degroote, Jan Vierendeels   +3 more
doaj   +1 more source

Waves in arteries: A review of wave intensity analysis in the systemic and coronary circulations

Artery Research, 2008
The intermittent ejection of blood by the ventricle results in pulsatile pressure and flow waveforms in the circulation. Understanding and characterizing this pulsatile behaviour is attracting increasing clinical interest, as it may have important implications for risk prediction and the mechanisms of action of therapeutic agents.
Alun D. Hughes, Kim H. Parker, Justin E. Davies   +2 more
openaire   +2 more sources

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Wave intensity analysis [PDF]

, 2014
Analiza wave intensity (WI) jest narzędziem do kompleksowej oceny funkcji układu krążenia. WI jest iloczynem prędkości i ciśnienia krwi przepływającej przez tętnicę w kolejnych interwałach czasowych.
Jaroch, Joanna; Oddział kardiologiczny Dolnośląskiego Szpitala Specjalistycznego im. T. Marciniaka we Wrocławiu, Rychard, Wojciech; Oddział kardiologiczny Dolnośląskiego Szpitala Specjalistycznego im. T. Marciniaka we Wrocławiu, Łoboz-Grudzień, Krystyna; Oddział kardiologiczny Dolnośląskiego Szpitala Specjalistycznego im. T. Marciniaka we Wrocławiu, Wydział Nauk o Zdrowiu, Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu   +2 more
core   +1 more source

2.6 FEASIBILITY OF AORTIC WAVE INTENSITY ANALYSIS FROM SEQUENTIALLY ACQUIRED CARDIAC MRI AND NON-INVASIVE CENTRAL BLOOD PRESSURE

Artery Research, 2018
Background: Wave intensity analysis (WIA) in the aorta offers important clinical and mechanistic insights but is difficult non-invasively. We performed WIA by combining high temporal resolution cardiovascular magnetic resonance (CMR) flow velocity and ...
Anish Bhuva, Niro Nadarajan, Andrew D’Silva, Camilla Torlasco, Redha Boubertakh, Siana Jones, Paul Scully, Rachel Bastiaenen, Guy Lloyd, Sanjay Sharma, James Moon, Kim Parker, Charlotte Manisty, Alun Hughes   +13 more
doaj   +1 more source