Results 41 to 50 of about 4,356,519 (301)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Site Characterization by Dynamic In Situ and Laboratory Tests for Liquefaction Potential Evaluation during Emilia Romagna Earthquake

Geosciences, 2018
To investigate the geotechnical soil properties of Emilia Romagna Region, a large series of in situ tests, laboratory tests and geophysical tests have been performed, particularly at the damaged city of Scortichino—Bondeno.
Antonio Cavallaro, Piera Paola Capilleri, Salvatore Grasso   +2 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Field Tests for Generating Source System and Picking the Seismic Shear Waves to Meet the Engineering Purposes Requirements. [PDF]

Kirkuk Journal of Science, 2019
Many seismic field tests were carried for the designed and modified seismic apparatuses using to generate seismic shear waves. These apparatus includes: "wooden plank" horizontal traction shear wave source, and a modified geophone for picking the SH-Wave
Muhana Ahmed
doaj   +1 more source

Built-In Self-Test for Static ADC Testing with a Triangle-Wave

IEICE Transactions on Electronics, 2013
SUMMARY This paper proposes a new BIST (Built-In Self-Test) method for static testing of an ADC (Analog-to-Digital Converter) with transition detection method. The proposed BIST uses a triangle-wave as an input test stimulus and calculates the ADC’s static parameters.
KIM, Incheol, LEE, Ingeol, KANG, Sungho
openaire   +2 more sources

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Experimental investigation on dynamic compaction for reinforcement of liquefiable sandy silt foundation

矿业科学学报
In light of the significant presence of liquefiable sandy silt layers in the foundation of the airfield area at the Beijing Daxing airport, this study employed a low-energy, small spacing, and low blow count dynamic compaction method to treat it.To ...
WANG Jialei, ZHANG Heqing, YU Qian, HAN Jinbao, LIU Yang, YAO Miaoxian   +5 more
doaj   +1 more source

The SSG Wave Energy Converter: Performance, Status and Recent Developments

Energies, 2012
The Sea-wave Slot-cone Generator (SSG) is a Wave Energy Converter based on the wave overtopping principle; it employs several reservoirs placed on top of each other, in which the energy of incoming waves is stored as potential energy.
Mariano Buccino, Diego Vicinanza, Lucia Margheritini, Jens Peter Kofoed   +3 more
doaj   +1 more source