Results 211 to 220 of about 9,355,325 (300)

Graph-based modeling of optical system enables adaptive optics on dynamic samples with self-calibration. [PDF]

open access: yesiScience
Cho ES   +8 more
europepmc   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti   +2 more
wiley   +1 more source

An eikonal model with re‐excitability for fast simulations in cardiac electrophysiology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Restitution properties obtained from cable‐equation simulations and anisotropic remeshing informed by local fibre orientation are combined in an eikonal model with re‐excitability. The resulting reduced electrophysiology model enables efficient simulations of recurrent activation patterns, here illustrated by atrial re‐entry ...
Lia Gander   +3 more
wiley   +1 more source

Influence of Mold Design and Molding Conditions on the Optical Properties of Contact Lenses. [PDF]

open access: yesSensors (Basel)
Tatsumi K   +6 more
europepmc   +1 more source

Electrodiffusion in cardiac intercalated disc nanostructures alters cell–cell action potential transmission via ephaptic coupling: A model study

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Ephaptic phenomena in a high‐resolution model of the cardiac intercalated disc. Meshed representation of a tortuous intercalated disc that was generated based on electron and super‐resolution microscopy data. Na+ channels (red) and gap junctions (green) are heterogeneously distributed, with additional regions of reduced ion ...
Ena Ivanovic   +4 more
wiley   +1 more source

The multicellular environment of the re‐entrant circuit in post‐myocardial infarction ventricular tachycardia: Beyond fibrosis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the temporal evolution of the post‐myocardial infarction substrate leading to ventricular tachycardia. Acute ischaemic injury initiates metabolic and electrophysiological disruption, followed by progressive inflammatory, fibrotic and structural remodelling within the infarct border zone.
Mohammed Obeidat   +6 more
wiley   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò   +18 more
wiley   +1 more source

Wavefront curvature sensing and control in microscopy

open access: yes
The purposes are multiples: creation of a wavefront curvature sensor, use of the curvature sensing to control a multi-actuator lens developed at CNR-IFN of Padua (18 piezoelectric actuators) and use of the multi-actuator lens to generate an astigmatic wavefront in order to obtain a 3D image by a single 2D image of the sample in examination.
openaire   +1 more source

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