Results 101 to 110 of about 5,982 (227)

Electrodiffusion in cardiac intercalated disc nanostructures alters cell–cell action potential transmission via ephaptic coupling: A model study

The Journal of Physiology, EarlyView.
Abstract figure legend Ephaptic phenomena in a high‐resolution model of the cardiac intercalated disc. Meshed representation of a tortuous intercalated disc that was generated based on electron and super‐resolution microscopy data. Na+ channels (red) and gap junctions (green) are heterogeneously distributed, with additional regions of reduced ion ...
Ena Ivanovic, Marina Vannucci, Nicolae Moise, Seth H. Weinberg, Jan P. Kucera   +4 more
wiley   +1 more source

Photonic integrated circuits for astronomy: A formal description of an integrated photonics-based wavefront sensor (IP-WFS)

Astronomy & Astrophysics
Context. Solar wavefront sensing has been a challenge for astrophysical instrumentalists, due to the low contrast between the Sun and the sky background compared to night-time observations, which limits the performance of adaptive optics systems.
Portero-Rodríguez D., García-Vázquez H., Díaz García J. J., Rodríguez Ramos L. F., Gracia Témich F., Aguerri J. Alfonso L.   +5 more
doaj   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Experimental Study on Wavefront Distortion Correction in Atmospheric Turbulence Using Zernike-Wavelet Hybrid Basis

Applied Sciences
In adaptive optics systems, most methods rely on reconstruction techniques centered on regional or global orthogonal bases, which struggle to accommodate the multi-scale characteristics of atmospheric turbulence wavefronts.
Jingyuan Liang, Yilin Hao, Hui Li, Xizheng Ke   +3 more
doaj   +1 more source

Panoramic voltage‐sensitive optical mapping of contracting hearts using cooperative multiview motion tracking with 12 cameras

The Journal of Physiology, EarlyView.
Abstact figure legend A panoramic 3D optical mapping system was developed, enabling imaging of action potential waves across the entire strongly deforming ventricular surface of beating isolated hearts. The system comprises 12 high‐speed cameras and a soccerball‐shaped imaging chamber with 48 light‐emitting diodes (LEDs).
Shrey Chowdhary, Jan Lebert, Shai Dickman, Mason Manetta, Charles Gordon, Jan Christoph   +5 more
wiley   +1 more source

Multiscale mechanistic modelling of heterogeneity in cardiac sub‐cellular calcium handling accounting for variable t‐system density

The Journal of Physiology, EarlyView.
Abstract figure legend Illustration of spatial calcium dynamics (left panels) and the state cycle approximation (middle panel) that enables reduced simulation of spatially dependent dynamics without explicit description of space (right panels). The selected example here illustrates a spontaneous calcium wave, showing temporal snapshots of local calcium
Michael A Colman, Yohannes Shiferaw, David Conesa   +2 more
wiley   +1 more source

Comparative multimodal calibration of patient‐specific atrial fibrillation models: Impact of imaging and electrophysiology data on arrhythmogenic substrate identification

The Journal of Physiology, EarlyView.
Abstract figure legend Comparative multimodal calibration of patient‐specific left atrial (LA) models to identify arrhythmogenic substrates in atrial fibrillation (AF). A, LA models shown in posterior and anterior views, calibrated separately using: late gadolinium enhancement magnetic resonance imaging (LGE‐MRI) image intensity ratio (IIR; blue–red ...
Mahmoud Ehnesh, Haseeb Valli, Ovais A. Jaffery, Sam Coveney, Alexander Zolotarev, Zhong Chen, Wajid Hussain, David G. Jones, Raad Mohiaddin, Tom Wong, Gregory Slabaugh, Steven A. Niederer, Edward Vigmond, Shouvik Haldar, Caroline Roney   +14 more
wiley   +1 more source

Visual outcome after correcting the refractive error of large pupil patients with wavefront-guided ablation

Clinical Ophthalmology, 2012
Mounir A Khalifa,1,2 Waleed A Allam,1,2 Mohamed S Shaheen2,31Ophthalmology Department, Tanta University Eye Hospital, Tanta, Egypt; 2Horus Vision Correction Center, Alexandria, Egypt; 3Ophthalmology Department, Alexandria University, Alexandria ...
Khalifa MA, Allam WA, Shaheen MS
doaj  

Adaptive wavefront correction structured illumination holographic tomography. [PDF]

Sci Rep, 2019
Balasubramani V, Tu HY, Lai XJ, Cheng CJ.   +3 more
europepmc   +1 more source

Semi‐Automated μCT‐Based Modeling of Vertebral Bony Endplate Microporosity and Mechanical Properties: Linking Microstructure to Inferred Mechanical Performance

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACT Background The vertebral bony endplate (BEP) plays a role in regulating both mechanical load transfer and nutrient transport to the intervertebral disc, functions strongly influenced by its microstructural porosity. Variations in porosity impact bone strength, elasticity, and solute diffusion, affecting its overall mechanical competence ...
Ahmad Alminnawi, Gabriele Nasello, Katherine B. Crump, Benjamin Gantenbein, Jerome Noailly, Liesbet Geris   +5 more
wiley   +1 more source