Results 191 to 200 of about 1,039,039 (252)

A Stepwise ECG Algorithm to Resolve Identical Precordial Transition in Idiopathic Outflow Tract Ventricular Arrhythmias

open access: yesPacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background Accurate pre‐procedural differentiation of right (RVOT) versus left ventricular outflow tract (LVOT) origin in idiopathic outflow tract ventricular arrhythmias may facilitate procedural planning and mapping strategy. However, existing 12‐lead ECG criteria show variable performance and often fail to provide clear discrimination when ...
Elena Krackhardt   +6 more
wiley   +1 more source

The theoretical basis of reservoir pressure in arteries

open access: yesExperimental Physiology, EarlyView.
Abstract The separation of measured arterial pressure into a reservoir pressure and an excess pressure was introduced over 20 years ago as a heuristic hypothesis. Since then it has gained some traction through epidemiological studies that show that various measures of reservoir and excess pressure are independent risk factors for cardiovascular disease.
Kim H. Parker, Alun D. Hughes
wiley   +1 more source

The multicellular environment of the re‐entrant circuit in post‐myocardial infarction ventricular tachycardia: Beyond fibrosis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the temporal evolution of the post‐myocardial infarction substrate leading to ventricular tachycardia. Acute ischaemic injury initiates metabolic and electrophysiological disruption, followed by progressive inflammatory, fibrotic and structural remodelling within the infarct border zone.
Mohammed Obeidat   +6 more
wiley   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò   +18 more
wiley   +1 more source

Panoramic voltage‐sensitive optical mapping of contracting hearts using cooperative multiview motion tracking with 12 cameras

open access: yesThe Journal of Physiology, EarlyView.
Abstact figure legend A panoramic 3D optical mapping system was developed, enabling imaging of action potential waves across the entire strongly deforming ventricular surface of beating isolated hearts. The system comprises 12 high‐speed cameras and a soccerball‐shaped imaging chamber with 48 light‐emitting diodes (LEDs).
Shrey Chowdhary   +5 more
wiley   +1 more source

Multiscale mechanistic modelling of heterogeneity in cardiac sub‐cellular calcium handling accounting for variable t‐system density

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Illustration of spatial calcium dynamics (left panels) and the state cycle approximation (middle panel) that enables reduced simulation of spatially dependent dynamics without explicit description of space (right panels). The selected example here illustrates a spontaneous calcium wave, showing temporal snapshots of local calcium
Michael A Colman   +2 more
wiley   +1 more source

Comparative multimodal calibration of patient‐specific atrial fibrillation models: Impact of imaging and electrophysiology data on arrhythmogenic substrate identification

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Comparative multimodal calibration of patient‐specific left atrial (LA) models to identify arrhythmogenic substrates in atrial fibrillation (AF). A, LA models shown in posterior and anterior views, calibrated separately using: late gadolinium enhancement magnetic resonance imaging (LGE‐MRI) image intensity ratio (IIR; blue–red ...
Mahmoud Ehnesh   +14 more
wiley   +1 more source

All-optical closed-loop control of human cardiomyocyte networks exploiting holographic optogenetics. [PDF]

open access: yesCommun Eng
Wendland R   +7 more
europepmc   +1 more source

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