Results 211 to 220 of about 562,479 (274)

Optical power profiles and aberrations of a non-diffractive wavefront-shaping extended depth of focus intraocular lens. [PDF]

Graefes Arch Clin Exp Ophthalmol
Garzón N, Gómez-Pedrero JA, Albarrán-Diego C, Fernández-Núñez S, Villanueva Gómez-Chacón S, García-Montero M.   +5 more
europepmc   +1 more source

The theoretical basis of reservoir pressure in arteries

Experimental Physiology, EarlyView.
Abstract The separation of measured arterial pressure into a reservoir pressure and an excess pressure was introduced over 20 years ago as a heuristic hypothesis. Since then it has gained some traction through epidemiological studies that show that various measures of reservoir and excess pressure are independent risk factors for cardiovascular disease.
Kim H. Parker, Alun D. Hughes
wiley   +1 more source

Advancing wavefront shaping with resonant nonlocal metasurfaces: beyond the limitations of lookup tables. [PDF]

Sci Rep
Isnard E, Héron S, Lanteri S, Elsawy M.
europepmc   +1 more source

Electrodiffusion in cardiac intercalated disc nanostructures alters cell–cell action potential transmission via ephaptic coupling: A model study

The Journal of Physiology, EarlyView.
Abstract figure legend Ephaptic phenomena in a high‐resolution model of the cardiac intercalated disc. Meshed representation of a tortuous intercalated disc that was generated based on electron and super‐resolution microscopy data. Na+ channels (red) and gap junctions (green) are heterogeneously distributed, with additional regions of reduced ion ...
Ena Ivanovic, Marina Vannucci, Nicolae Moise, Seth H. Weinberg, Jan P. Kucera   +4 more
wiley   +1 more source

The multicellular environment of the re‐entrant circuit in post‐myocardial infarction ventricular tachycardia: Beyond fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the temporal evolution of the post‐myocardial infarction substrate leading to ventricular tachycardia. Acute ischaemic injury initiates metabolic and electrophysiological disruption, followed by progressive inflammatory, fibrotic and structural remodelling within the infarct border zone.
Mohammed Obeidat, Jaffar Al‐Sheikhli, Andrew M. Blanks, Joseph Mayer, Nicolas Lellouche, Tarvinder Dhanjal, Christopher O'Shea   +6 more
wiley   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Panoramic voltage‐sensitive optical mapping of contracting hearts using cooperative multiview motion tracking with 12 cameras

The Journal of Physiology, EarlyView.
Abstact figure legend A panoramic 3D optical mapping system was developed, enabling imaging of action potential waves across the entire strongly deforming ventricular surface of beating isolated hearts. The system comprises 12 high‐speed cameras and a soccerball‐shaped imaging chamber with 48 light‐emitting diodes (LEDs).
Shrey Chowdhary, Jan Lebert, Shai Dickman, Mason Manetta, Charles Gordon, Jan Christoph   +5 more
wiley   +1 more source

Multiscale mechanistic modelling of heterogeneity in cardiac sub‐cellular calcium handling accounting for variable t‐system density

The Journal of Physiology, EarlyView.
Abstract figure legend Illustration of spatial calcium dynamics (left panels) and the state cycle approximation (middle panel) that enables reduced simulation of spatially dependent dynamics without explicit description of space (right panels). The selected example here illustrates a spontaneous calcium wave, showing temporal snapshots of local calcium
Michael A Colman, Yohannes Shiferaw, David Conesa   +2 more
wiley   +1 more source

Clinical Outcomes after Bilateral Implantation of a Wavefront-Shaping Extended Depth of Focus (EDOF) IOL with Mini-Monovision. [PDF]

J Clin Med
Won YK, Choi SH, Chung TY, Lim DH.
europepmc   +1 more source

Comparative multimodal calibration of patient‐specific atrial fibrillation models: Impact of imaging and electrophysiology data on arrhythmogenic substrate identification

The Journal of Physiology, EarlyView.
Abstract figure legend Comparative multimodal calibration of patient‐specific left atrial (LA) models to identify arrhythmogenic substrates in atrial fibrillation (AF). A, LA models shown in posterior and anterior views, calibrated separately using: late gadolinium enhancement magnetic resonance imaging (LGE‐MRI) image intensity ratio (IIR; blue–red ...
Mahmoud Ehnesh, Haseeb Valli, Ovais A. Jaffery, Sam Coveney, Alexander Zolotarev, Zhong Chen, Wajid Hussain, David G. Jones, Raad Mohiaddin, Tom Wong, Gregory Slabaugh, Steven A. Niederer, Edward Vigmond, Shouvik Haldar, Caroline Roney   +14 more
wiley   +1 more source