Results 161 to 170 of about 41,547 (285)

On-chip wavelength division multiplexing by angled multimode interferometer fabricated on erbium-doped thin film lithium niobate on insulator. [PDF]

Nanophotonics
Han J, Bao R, Wu R, Liu Z, Wang Z, Sun C, Zhang Z, Li M, Fang Z, Wang M, Zhang H, Cheng Y.   +11 more
europepmc   +1 more source

Fiber Bragg Grating Force Sensors for Minimally Invasive Surgery: State of the Art, Challenges, and Opportunities

SmartBot, EarlyView.
This article reviews the application of fiber Bragg grating (FBG) technology for precise force sensing in minimally invasive surgery. It outlines the fundamental working principles and algorithms used to interpret sensor data. The text surveys clinical applications across various medical fields, such as ophthalmology and vascular intervention (Table of
Shiyuan Dong, Tianqi Huang, Lingyu Chen, Shucong Yin, Qing Chang, Dingpei Han, Yangxi Li, Boyu Zhang, Hongen Liao, Fang Chen   +9 more
wiley   +1 more source

Human Colitis‐on‐Chip Model Reveals Dual Roles of Butyrate in Epithelial and Macrophage Defense Against Candida albicans Tissue Invasion

Small, EarlyView.
This study establishes a human immunocompetent colitis‐on‐chip model that mimics inflamed gut mucosa and enables quantitative analysis of Candida albicans tissue invasion under DSS‐induced injury. It reveals that microbiota‐derived butyrate simultaneously stabilizes epithelial junctions and reprograms macrophages via HDAC/NLRP3‐dependent mechanisms ...
Manuel Allwang, Maximilian Wipplinger, Parastoo Akbarimoghaddam, Raquel Alonso‐Roman, Zoltan Cseresnyes, Axel Dietschmann, Valentin Wegner, Adrian Feile, Yann Bachelot, Maria Warschinke, Mohamed I. Abdelwahab Hassan, Sonnhild Mittag, Otmar Huber, Bernhard Hube, Mark S. Gresnigt, Marc Thilo Figge, Alexander S. Mosig   +16 more
wiley   +1 more source

SERS‐Based Nano‐ and Microsystems Toward Biomedical Applications

Small, EarlyView.
This review provides a current overview of nano‐ and microscale SERS‐based devices, encompassing all aspects from material design to practical applications. We highlight controlled SERS‐active architectures, including patterned substrates, nanorods, microspheres, micromotors, and microneedles, as well as combinations of these microfluidic systems.
Gohar Soufi, Tijana Maric, Isidro Badillo‐Ramírez, Juliane Fjelrad Christfort, Matteo Tollemeto, Carmen Milan Guimera, Casper Nisula, Giulia Zappalá, Laura De Vittorio, Marta Rubio‐Huertas, Sungyeong Kim, Ziqiao Li, Morten Bo Søndergaard Svendsen, Zhongyang Zhang, Anja Boisen   +14 more
wiley   +1 more source

Scalable Room‐Temperature Terahertz Graphene Cameras

Small Methods, EarlyView.
ABSTRACT Terahertz (THz) imaging has emerged as a powerful tool for non‐destructive, label‐free analysis across several scientific disciplines, ranging from materials science to biomedical research. By capturing the spatial‐dependent information in a broad range of frequencies, this technique enables the identification of chemical composition ...
Lili Shi, Leonardo Viti, Miriam S. Vitiello   +2 more
wiley   +1 more source

Contact sensitisers activate keratinocytes and induce cytotoxicity via Transient Receptor Potential Ankyrin 1 in allergic contact dermatitis

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Allergic contact dermatitis (ACD) is a frequent inflammatory skin disease with limited therapeutic options. While neuronal Transient Receptor Potential Ankyrin 1 (TRPA1) has been implicated in ACD, the role of keratinocyte TRPA1 remains unclear.
Areej Jaber, Szabina Horváth, Balázs Zoltán Zsidó, Viktória Kormos, János Konkoly, Csaba Hetényi, Erika Pintér, Ágnes Kemény, Rolland Gyulai   +8 more
wiley   +1 more source

Multiplexed Transcriptomics for Screening Drug Combinations and Defining the Mechanism of Action of HCC Therapeutics at Single‐Cell Resolution

Cell Proliferation, EarlyView.
We designed a framework for screening clinical drug combinations with anti‐hepatocellular carcinoma (HCC) activity, comprising four parts: primary screening, single‐cell screening, functional validation, and mechanism research. High‐throughput single‐cell screening identifies HY (HHT and YM155) as a potent anti‐HCC drug combination, validated by in ...
Mengmeng Jiang, Haide Chen, Guoxia Wen, Yuqing Mei, Wenzhao Zhou, Bin Xu, Tingyue Zhang, Guangyan Li, Junqing Wu, Xiaoping Han, Xudong Fu, Guoji Guo, Jingjing Wang   +12 more
wiley   +1 more source

The “Tianyu” Formulation Alleviates Rheumatoid Arthritis by Modulating the NLRP3/Caspase‐1/GSDMD‐Mediated Pyroptosis Pathway

The FASEB Journal, Volume 40, Issue 9, 15 May 2026.
Proposed signaling pathway by which TY modulates NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis. ABSTRACT This research focuses on exploring the modulation of pyroptosis and its underlying mechanisms via the “Tianyu” formulation (TY), a traditional Chinese medicine, in human rheumatoid arthritis fibroblast‐like synovial cells (RA‐HFLS) and a collagen ...
Yueya Zhu, Xinying Cai, Qiuhan Zheng, Chunqiu Fang, Zhi Pan, Yinghang Wang   +5 more
wiley   +1 more source

Lithium Niobate Quadratic Integrated Nonlinear Photonics: Enabling Ultra‐Wide Bandwidth and Ultrafast Photonic Engines

Nanophotonics, Volume 15, Issue 9, 13 May 2026.
This perspective surveys emerging quantum and classical photonic applications across operating wavelengths and timescales, highlighting persistent technological gaps in integrated light sources. We examine the unique advantages of quadratic nonlinear photonics on the thin‐film lithium niobate (TFLN) platform and discuss strategies for realizing ...
Meng Tian, Guanyu Han, Ziyao Feng, Yu Liu, Yu Wang, Wenjun Deng, Ayed Al Sayem, Qiushi Guo   +7 more
wiley   +1 more source

Terahertz Metasurface for Spatial Detection of Full Stokes Parameters and Polarization Imaging

Nanophotonics, Volume 15, Issue 9, 13 May 2026.
This work presents a THz polarization analyzer with significantly improved robustness against nonuniformity. By integrating four polarization‐sensitive meta‐atoms into a meta‐cell, the metalens splits incident light into six polarization components and generates off‐axis focal spots.
Shengnan Guan, Jierong Cheng, Haifeng Xu, Fan Li, Chenglong Liu, Shengjiang Chang   +5 more
wiley   +1 more source