Results 71 to 80 of about 41,120 (294)

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Silicon photonic transmitter and receiver for hybrid multiplexing systems

Chip
High-capacity on-chip optical transmitters and receivers are crucial for data transmissions. Currently, advanced multiplexing technologies, including wavelength division multiplexing (WDM), mode-division multiplexing (MDM), and polarization-division ...
Yingying Peng, Hengzhen Cao, Jin Xie, Weike Zhao, Yuluan Xiang, Dajian Liu, Zejie Yu, Daoxin Dai   +7 more
doaj   +1 more source

Algorithm for Implementation of Wavelength Division Multiplexing in EPON [PDF]

Telfor Journal, 2010
Today, implementation of wavelength division multiplexing in the Ethernet passive optical network (EPON) is considered as one of the most perspective solutions for the bottleneck problem in the access network. With the development of new applications and
P. S. Matavulj, M. R. Radivojević
doaj  

A Compact Low-Power 320-Gb/s WDM Transmitter Based on Silicon Microrings

IEEE Photonics Journal, 2014
We demonstrate a compact and low-power wavelength-division multiplexing transmitter near a 1550-nm wavelength using silicon microrings. The transmitter is implemented on a silicon-on-insulator photonics platform with a compact footprint of 0.5 mm2.
Ran Ding, Yang Liu, Qi Li, Zhe Xuan, Yangjin Ma, Yisu Yang, Andy Eu-Jin Lim, Guo-Qiang Lo, Keren Bergman, Tom Baehr-Jones, Michael Hochberg   +10 more
doaj   +1 more source

Deterministic Raman crosstalk effects in amplified wavelength division multiplexing transmission

, 2010
We study the deterministic effects of Raman-induced crosstalk in amplified wavelength division multiplexing (WDM) optical fiber transmission lines. We show that the dynamics of pulse amplitudes in an N-channel transmission system is described by an N ...
Abas, Agrawal, Al-Qazwini, Ania-Castañón, Avner Peleg, Chi, Chraplyvy, Christodoulides, Chung, Chung, Colella, Cotter, Cuenot, Daikoku, Evangelides, Forghieri, Gnauck, Gnauck, Gnauck, Gordon, Grosz, Headley, Hirsch, Ho, Iannone, Kim, Kim, Kodama, Kumar, Lakoba, Malomed, Malomed, Mazroa, Mazurczyk, Mitschke, Mollenauer, Mollenauer, Mollenauer, Muktoyuk, Peleg, Peleg, Peleg, Peleg, Peleg, Quan M. Nguyen, Rasmussen, Sarkar, Stolen, Stolen, Vanholsbeeck, Wiggins, Xu, Xu, Yamamoto, Zakharov, Zhou   +55 more
core   +1 more source

Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy

Advanced Science, EarlyView.
Autoantibodies against fibroblast growth factor receptor 3 (FGFR3) are identified as pathogenic drivers of pain in small fiber neuropathy. By binding to sensory neurons in dorsal root ganglia, FGFR3 autoantibodies activate MAPK signaling and induce hyperexcitability and mechanical hypersensitivity, establishing FGFR3 autoantibodies as a therapeutic ...
Lyuba Y. Salih, Nicolas L.A. Dumaire, Clémence Gieré, Erin Vest, Haya Alkhateeb, Christian P. Moritz, Yannick Tholance, Jean‐Philippe Camdessanché, Jean‐Christophe Antoine, Jérôme Honnorat, Jafar Kafaie, Liberty François‐Moutal, Aubin Moutal   +12 more
wiley   +1 more source

Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System

Advanced Science, EarlyView.
This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi, Weiqi Ge, Changheng Li, Bin Liu, Xiaoyi Deng, Chengjie Liu, Meijun Zheng, Pu Zhang, Lei Li, Ying Guo, Yunqi Han, Yu Yang, Yanxun V. Yu, Youngnam N. Jin   +13 more
wiley   +1 more source

Design Reliable Bus Structure Distributed Fiber Bragg Grating Sensor Network Using Gated Recurrent Unit Network

Sensors, 2020
The focus of this paper was designing and demonstrating bus structure FBG sensor networks using intensity wavelength division multiplexing (IWDM) techniques and a gated recurrent unit (GRU) algorithm to increase the capability of multiplexing and the ...
Amare Mulatie Dehnaw, Yibeltal Chanie Manie, Ya Yu Chen, Po Han Chiu, Hung Wei Huang, Guan Wei Chen, Peng Chun Peng   +6 more
doaj   +1 more source

2x2 MIMO-OFDM Gigabit fiber-wireless access system based on polarization division multiplexed WDM-PON [PDF]

, 2012
We propose a spectral efficient radio over wavelength division multiplexed passive optical network (WDM-PON) system by combining optical polarization division multiplexing (PDM) and wireless multiple input multiple output (MIMO) spatial multiplexing ...
Agmon, Chen, Darko Zibar, Deming Liu, Idelfonso Tafur Monroy, Jansen, Jesper Bevensee Jensen, Kobyakov, Lei Deng, Liu, Liu, M. B. Othman, Othman, Sauer, Stuber, Tsukamoto, Xianbin Yu, Xiaodan Pang, Ying Zhao   +18 more
core   +2 more sources

Real‐Time Visualization of Isoform‐Specific RAF‐KRAS Interactions in Living Cells Using FRET‐BRET Hybrid Biosensors

Advanced Science, EarlyView.
Hybrid FRET–BRET biosensors were developed to monitor RAF–KRAS interactions in living cells. These sensors enable real‐time visualization of interaction dynamics, quantitative spectral analysis, and validation of mutation‐selective inhibitors, providing a versatile platform for probing KRAS regulation and therapeutic responses. ABSTRACT The RAS–RAF–MEK–
Jeong‐Min Go, Dahee Lee, Minji Kim, Kiseok Han, Gyuho Choi, ChanHui Song, Sanghyun Ahn, Yerim Lee, Jinyoung Lee, Yingxiao Wang, Jung‐Soo Suh, Hwayoung Yun, Tae‐Jin Kim   +12 more
wiley   +1 more source