Results 111 to 120 of about 476,480 (304)
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
BioResourcesThe objective of this study was to synthesize flame-retardant wax by nano-sizing a previously developed flame-retardant with favorable performance characteristics.
Hyung Woo Lee +4 more
doaj
Auroral rocket experiment 2 Final report [PDF]
Detecting fluxes of energetic neutral hydrogen atoms in interplanetary medium by auroral rocket ...
Bernstein, W., Inouye, G. T., Wax, R. L.
core +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2015 Bu deneysel çalışmada, katkısız poliamid 6 (PA 6), %15 grafit katkılı poliamid 6 (PA6-15G) kompozit ve %15 grafit ve %6 vaks katkılı poliamid 6 (PA6-15G-6W).
Hüseyin Ünal, Salih Yetgin
doaj
Automotive e-Fuels via Hydrocracking of FT-Wax: e-Gasoline and e-Diesel Production
EnergiesThe main goal of this research is the production of e-fuels in gasoline- and diesel-range hydrocarbons via the hydrocracking of wax from Fischer–Tropsch (FT-wax) synthesis. The hydrogen for the hydrocracking process originated from solar energy via water
Athanasios Dimitriadis +2 more
doaj +1 more source