Results 41 to 50 of about 776,308 (247)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Wax Formation Mechanisms, Wax Chemical Inhibitors and Factors Affecting Chemical Inhibition

open access: yesApplied Sciences, 2020
When crude oil is extracted out of a subterranean reservoir at high temperature and pressure, it is usually transported via a pipeline, where the crude oil experiences radical changes in its physical and chemical properties, instigating numerous ...
Thevaruban Ragunathan   +2 more
doaj   +1 more source

National Atmospheric Deposition Program 2015 Annual summary [PDF]

open access: yes, 2016
The National Atmospheric Deposition Program (NADP) provides fundamental measurements that support informed decisions on environmental issues related to precipitation and atmospheric deposition chemistry, as well as atmospheric mercury and ammonia.

core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

An In-depth Experimental Study of Wax Deposition in Pipelines [PDF]

open access: yes
Shale oils are highly paraffinic and, consequently, can create wax deposits that foul pipelines during transportation. Several factors must be considered when designing pipelines or treatmentprograms that prevent wax deposition: including chemical ...
Raffo, Pablo Alejandro   +5 more
core   +1 more source

National Atmospheric Deposition Program 2014 Annual Summary [PDF]

open access: yes, 2015
The National Atmospheric Deposition Program (NADP) provides fundamental measurements that support informed decisions on environmental issues related to precipitation and atmospheric deposition chemistry, as well as atmospheric mercury and ammonia.

core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Wax Deposition of Diesel Oil and Consequent Contamination of Gasoline in Sequential Transportation of Product Oil Pipeline

open access: yesEnergies
Wax deposition of diesel oil and contamination of gasoline by diesel wax deposit is a severe problem in sequential transportation of product oil in pipes. However, it has long been neglected by the pipeline transportation industry. In response, this work
Weidong Li   +7 more
doaj   +1 more source

Mathematical Modeling of Wax Deposition in Field-Scale Crude Oil Pipeline Systems

open access: yesJournal of Applied Mathematics, 2022
The formation of solid wax crystals, which interlock and form a gel-like layer on the inner wall of the crude oil pipeline, influences the transportation of waxy crude oil. The deposited layer grows continuously and hardens during the oil transportation,
Francis Oketch Ochieng   +3 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

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