Results 61 to 70 of about 1,252,422 (303)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Remembering and belonging : colonial settlers in New Zealand museums : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Social Anthropology at Massey University [PDF]

, 2007
This study approaches museums as socially constructed signifiers of group identities. Focusing specifically on museological representations of colonial settlers at museums and historical sites in New Zealand, I analyse how this group is constructed in ...
Wirick, Esther Lucia
core  

Stop the Clock! Taking the Nation out of Linear Time and Bounded Space [PDF]

, 2019
This article focuses on the importance of linear time and bounded space to the nation, which must have a past, present and future in a way that occludes other ways of grasping time.
Sutherland, Claire
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Practicing Home in the Foreign: 'The multiple homing practices of artisan journeymen on the tramp'

Nordic Journal of Migration Research, 2018
Research in migrant practices has recognised that home crystallises into multiple forms subject to constant re-enactment when viewed from the perspective of mobile populations such as nomads and refugees.
Dorte Jagetic Andersen, René Ejbye Pedersen   +1 more
doaj   +1 more source

G2 Dualities in D=5 Supergravity and Black Strings

, 2009
Five dimensional minimal supergravity dimensionally reduced on two commuting Killing directions gives rise to a G2 coset model. The symmetry group of the coset model can be used to generate new solutions by applying group transformations on a seed ...
Amitabh Virmani, Argurio R, Berkooz M, Bossard G Nicolai H Stelle K S, Bouchareb A, Caldarelli M M, Camps J, Clement G, Compère G de Buyl S Jamsin E Virmani A, Cremmer E Julia B Lu H Pope C N, Ehlers J, Ella Jamsin, Elvang H, Elvang H, Elvang H, Emparan R, Emparan R, Emparan R, Emparan R, Emparan R, Emparan R Harmark T Niarchos V Obers N A, Ford J, Gal'tsov D V Scherbluk N G, Gauntlett J P, Geoffrey Compère, Giusto S, Harmark T, Henneaux M, Horowitz Gary T, Houart L Kleinschmidt A Hörnlund J L Persson D Tabti N, Humphreys J E, Julia B, Kastor D, Peet A W, Pomeransky A A Sen'kov R A, Pope C, Sophie de Buyl, Tanabe M, Tomizawa S Yasui Y Ishibashi A, Tomizawa S Yasui Y Morisawa Y, Townsend P K, Yazadjiev S S   +41 more
core   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Mapping networks of influence: tracking Twitter conversations through time and space [PDF]

, 2015
The increasing use of social media around global news events, such as the London Olympics in 2012, raises questions for international broadcasters about how to engage with users via social media in order to best achieve their individual missions. Twitter
Fisher, Ali, Lvov, Ilia, Willis, Alistair   +2 more
core  

Orbital-resolved Soft X-Ray Spectroscopy in NaV2O5

, 2002
We demonstrate that angle-resolved soft x-ray spectroscopy can resolve absorption by inequivalent oxygen sites and by different orbitals belonging to the same site in NaV2O5.
Callcott, T. A., Chang, G. S., He, J., Lin, L., Mandrus, D., Sales, B. C., Shirley, Eric L., Woods, G. T., Zhang, G. P.   +8 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source