Results 81 to 90 of about 1,252,422 (303)

On the robustness of Herlihy's hierarchy [PDF]

, 1993
A wait-free hierarchy maps object types to levels in Z(+) U (infinity) and has the following property: if a type T is at level N, and T' is an arbitrary type, then there is a wait-free implementation of an object of type T', for N processes, using only ...
Jayanti, Prasad
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Gênero, mídia e recepção: sobre as narrativas televisivas e seus espectador

Cadernos de Estudos Lingüísticos, 2011
The main objective of this article is to describe some of the ways certain individuals belonging to an specific social group exibit their knowledge about the themes, composicional structure and functioning of a mass media genre: Brazilian soap operas.
Anna Christina Bentes, Ingedore Grunfeld Villaça Koch, Cássia Michela Alves Nogueira   +2 more
doaj   +1 more source

Songs of Mobility and Belonging: Gender, Spatiality and the Local in Southern Africa’s Transfrontier Conservation Development [PDF]

, 2013
Western Maputaland is located in the borderlands of South Africa, Mozambique and Swaziland. The combination of poverty, rural remoteness and exceptional ecological diversity has long made the region a target of conservationists and development planners ...
Impey, Angela
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

What Grounds Special Treatment Between Siblings?

Etikk i Praksis: Nordic Journal of Applied Ethics, 2020
Siblings ought to treat one another specially – in other words, siblings qua siblings ought to treat one another in ways that they need not treat others. This paper offers a theory of why this is the case.
Marcus William Hunt
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

The dependence of AGN activity on stellar and halo mass in Semi-Analytic Models

, 2010
AGN feedback is believed to play an important role in shaping a variety of observed galaxy properties, as well as the evolution of their stellar masses and star formation rates.
Adelman-McCarthy, Anna Pasquali, Baldwin, Barnes, Barnes, Barton, Baugh, Becker, Bell, Bertschinger, Best, Binney, Binney, Blanton, Bower, Bower, Boylan-Kolchin, Brinchmann, Bîrzan, Cattaneo, Condon, Cox, Croton, De Lucia, De Lucia, Dekel, Di Matteo, Fabio Fontanot, Fanidakis, Ferrarese, Fontanot, Fontanot, Fontanot, Frank C. van den Bosch, Gabriella De Lucia, Ganguly, Gebhardt, Georgakakis, Granato, Granato, Hardcastle, Heckman, Hopkins, Hopkins, Hopkins, Hopkins, Hopkins, Häring, Jester, Jiang, Jiang, Jing, Kaiser, Kang, Kang, Kang, Kauffmann, Kauffmann, Kauffmann, Kennicutt, Khochfar, Kimm, Kormendy, Li, Lin, Magorrian, Marconi, Marconi, McNamara, Monaco, Monaco, Monaco, Monaco, Negroponte, Nulsen, Pasquali, Pasquali, Pasquali, Peng, Pounds, Rachel S. Somerville, Robertson, Ruszkowski, Sanders, Schawinski, Shankar, Sijacki, Simpson, Somerville, Somerville, Taffoni, Umemura, van den Bosch, Volonteri, Walker, Wang, Wang, Weinmann, Weinmann, Willott, Woods, Wu, Xi Kang, Yang, Yang, Yang, Zheng   +106 more
core   +1 more source

An occupational perspective of the lived experience of familial dementia caregivers : a thematic review of qualitative literature [PDF]

, 2016
Dementia caregiving is thought to have a negative impact on health and wellbeing. This critical review of qualitative literature explored the lived experience of familial dementia caregivers from an occupational therapy perspective.
Alzheimer’s Society, College of Occupational Therapists, Emma K Hooper, Hek G., Joanna Briggs Institute, Kielhofner G., Silverman D., Tracy Collins, Turpin M., Watson R.   +9 more
core   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source