Results 141 to 150 of about 16,945 (287)

Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation

open access: yesAdvanced Science, EarlyView.
This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar   +10 more
wiley   +1 more source

Combining Spatial Multi‐Omics Data to Decipher Spatial Domains and Elucidate Cell Heterogeneity Based on Self‐Supervised Graph Learning

open access: yesAdvanced Science, EarlyView.
A self‐supervised multi‐view graph fusion framework integrates spatial multi‐omics, excelling in domain identification and denoising. It reconstructs spatial pseudo‐expression, jointly analyzes multi‐omics data, infers RNA velocity, predicts spatial omics features from single‐cell multi‐omics, and detects spatially dark genes and transcription factors,
Yuejing Lu   +8 more
wiley   +1 more source

Phase‐Resolved Defect Transport Mechanisms Governing Asynchronous Ordering in a Eutectic High‐Entropy Alloy

open access: yesAdvanced Science, EarlyView.
Phase‐resolved experiments and atomistic simulations reveal asynchronous ordering behaviors in a eutectic high‐entropy alloy during isothermal annealing. Distinct defect transport mechanisms are identified in coexisting B2 and BCC phases, showing that vacancy and interstitial mediated diffusion governs phase‐dependent thermal stability.
Huiwen Yao   +5 more
wiley   +1 more source

Approximation of stochastic differential equations driven by alpha-stable Levy motion [PDF]

open access: yes
In this paper we present a result on convergence of approximate solutions of stochastic differential equations involving integrals with respect to alpha-stable Levy motion.
Aleksander Janicki   +2 more
core  

Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning

open access: yesAdvanced Science, EarlyView.
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen   +6 more
wiley   +1 more source

Weak convergence of probability measures

open access: yes, 2007
Katedra pravděpodobnosti a matematické statistikyDepartment of Probability and Mathematical StatisticsFaculty of Mathematics and PhysicsMatematicko-fyzikální ...
Klicnarová, Jana
core  

STAID: A Self‐Refining Deep Learning Framework for Spatial Cell‐Type Deconvolution with Biologically Informed Modeling

open access: yesAdvanced Science, EarlyView.
STAID is a unified deep learning framework that couples iterative pseudo‐spot refinement with neural network training through a feedback loop and exploits gene co‐expression information to model higher‐order interactions, achieving accurate and robust cell‐type deconvolution in spatial transcriptomics.
Jixin Liu   +5 more
wiley   +1 more source

Efficient MCMC and posterior consistency for Bayesian inverse problems [PDF]

open access: yes
Many mathematical models used in science and technology often contain parameters that are not known a priori. In order to match a model to a physical phenomenon, the parameters have to be adapted on the basis of the available data.
Vollmer, Sebastian
core  

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