Results 211 to 220 of about 306,024 (298)

Metagenomic and gene expression patterns in declining commercial honey bee colonies. [PDF]

Sci Rep
Nearman A, Lamas ZS, Niño EL, Fine J, Mayack C, Seshadri A, Boncristiani D, Huang WF, Evans JD, Chen YP.   +9 more
europepmc   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Urban compactness and Land Use Efficiency in Indochina Capitals: A multi-method spatial assessment (2017-2024). [PDF]

PLoS One
Nguyen TT.
europepmc   +1 more source

LC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization

Advanced Science, EarlyView.
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang, Tan Wei, Jiahang Wu, Chuixu Lin, Dongbo Zhu, Yanhui Li, Shuting Shi, Shishun Huang, Leiming Jiang, Hongzhi Wang, Meiqi Song, Pengfei Gao, Xu Wu, Mingjian Fan, Chaofeng Wei, Qian Wang, Lihui Qu, Zhigang Wang   +17 more
wiley   +1 more source

Japanese clinical practice guidelines for vascular tumors, vascular malformations, lymphatic malformations, and lymphangiomatosis 2022. [PDF]

Jpn J Radiol
Kinoshita Y, Ishikawa K, Akita S, Koh K, Sasaki S, Jinnin M, Mimura H, Osuga K, Ozeki M, Nagahama M, Fujino A, Aoki Y, Asai A, Aramaki-Hattori N, Ishiura R, Inoue M, Iwashina Y, Ohshiro T, Ogawa K, Ozaki M, Ochi J, Onozawa S, Kato M, Kaneko T, Kawakami T, Kitagawa A, Kurita M, Kuwano Y, Kono T, Seike S, Takagi S, Takakura N, Tachibana T, Tanoue S, Chuman K, Nakaoka H, Nakamura Y, Nagai F, Niimi Y, Nosaka S, Nozaki T, Nomura T, Hashimoto K, Hayashi A, Hirakawa S, Hirabayashi T, Furukawa T, Furukawa H, Hori Y, Maekawa T, Matsuoka K, Mori H, Morii E, Morimoto A, Moriwaki Y, Yuzuriha S, Rikihisa N, Fujita M, Yamahana Y, Deie K, Tozawa A, Hasegawa D, Higashiyama A, Maeda D, Asayama S, Arai Y, Iwata Y, Uka M, Usui H, Uchiyama M, Endo S, Endo H, Ono R, Oshima N, Otsuka T, Ohara K, Kagami S, Kakihara T, Kato M, Kanamori H, Kamata M, Kawaguchi A, Kishi A, Kitagawa H, Kim K, Kobayashi T, Saito T, Shikano Y, Shimada S, Suzuki K, Takahashi M, Takami S, Takeda R, Tanaka A, Tanaka K, Tamura S, Tamura M, Danno K, Tsuboi K, Nakajima Y, Nakatani R, Noguchi M, Nozawa A, Hashizume N, Hayakawa M, Hayashi D, Fukumoto T, Honda M, Matsuda N, Maruguchi H, Murakami N, Yaguchi K, Yasue S, Yoshihara H, Yoshimatsu R, Yamamoto K, Wada S.   +116 more
europepmc   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Dispersive lensing and shadows in RN-AdS spacetimes with dark energy and plasma: theory and observational constraints. [PDF]

Sci Rep
Pradhan A, Ghaderi K, Zeyauddin M.
europepmc   +1 more source

Laser‐Induced Ultrafast Magnetic Phase Transition in 2D Van Der Waals Antiferromagnetic Heterostructures

Advanced Science, EarlyView.
In this work, ultrafast laser‐induced spin transfer and spin relaxation dynamics in 2D van der Waals antiferromagnetic CrI3/CrGeTe3 heterostructures are investigated. Laser excitation is demonstrated to induce pronounced interlayer nonequilibrium spin dynamics and ultrafast magnetic moment reconstruction, driving a transition from an antiferromagnetic (
Yang Wu, Fulu Zheng, San‐Dong Guo, Thomas Frauenheim, Zhaobo Zhou, Junjie He   +5 more
wiley   +1 more source

Resuscitative thoracotomy in traumatic cardiac arrest : Multisociety consensus recommendations for settings with a low prevalence of penetrating injuries. [PDF]

Wien Klin Wochenschr
Dünser MW, Grassmann D, Hamp T, Krammel M, Eller P, Eisenburger P, Erblich R, Hallmann B, Halmich M, Hellwagner K, Herbich K, Herkner H, Knez I, Negrin LL, Rigaud M, Schlieber J, Schnaubelt S, Schreiber W, Stommel AM, Tomaselli F, Trimmel H, Veigl C, Voelckel W, Watzka S, Wiedemann D, Puchwein P.   +25 more
europepmc   +1 more source

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

Advanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu, Shuhao Chen, Yunheng Diao, Wei Wang, Yuanyuan Huang, Liqin Liang, Xiaodan Lu, Rui Han, Minxin Guo, Zhaobo Li, Shuhong Wang, Hehua Li, Chenyu Liu, Jing Zhou, Dongsheng Xiong, Xiaobo Li, Yuping Ning, Xuetao Shi, Fengchun Wu, Kai Wu   +19 more
wiley   +1 more source