Results 21 to 30 of about 46,236 (223)

External Validation of the Lupus Multivariable Outcome Score for Systemic Lupus Erythematosus Trials

open access: yesACR Open Rheumatology, 2022
Objective Development of new systemic lupus erythematosus (SLE) treatments requires an effective responder index. Toward this end, we have recently developed a new Lupus Multivariable Outcome Score (LuMOS) to optimize discrimination between actively ...
Michal Abrahamowicz   +2 more
doaj   +1 more source

Phase Angle as an Early Functional Biomarker of Cancer‐Related Fatigue in Pediatric Oncology: A Prospective Longitudinal Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric cancer remains a leading cause of morbidity and mortality worldwide, particularly in low‐and middle‐income countries. Cancer treatment may impair nutritional status, alter body composition, and exacerbate cancer‐related fatigue (CRF).
Luís Carlos Lopes‐Junior   +11 more
wiley   +1 more source

q-Poincaré supersymmetry in AdS5/CFT4

open access: yesNuclear Physics B, 2018
We consider the exact S-matrix governing the planar spectral problem for strings on AdS5×S5 and N=4 super Yang–Mills, and we show that it is invariant under a novel “boost” symmetry, which acts as a differentiation with respect to the particle momentum ...
Riccardo Borsato, Alessandro Torrielli
doaj   +1 more source

Seasonality and landscape characteristics impact species community structure and temporal dynamics of East African butterflies

open access: yesScientific Reports, 2021
Species community structures respond strongly to habitat changes. These are either driven by nature or human activities. The biota of East African drylands responds highly sensitively to natural and anthropogenic impacts.
Thomas Schmitt   +4 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Observations and hypotheses related to low to middle free tropospheric aerosol, water vapor and altocumulus cloud layers within convective weather regimes: a SEAC4RS case study [PDF]

open access: yesAtmospheric Chemistry and Physics, 2019
The NASA Studies of Emissions and Atmospheric Composition, Clouds and Climate Coupling by Regional Surveys (SEAC4RS) project included goals related to aerosol particle life cycle in convective regimes.
J. S. Reid   +18 more
doaj   +1 more source

Composition and Source Identification of Nitrogen in Groundwater in an Urbanized Basin

open access: yesRedai dili, 2023
The Maquekengshui basin in Pingshan District of Shenzhen was selected as a case study to reveal the composition characteristics and sources of nitrogen in groundwater, with water samples collected from domestic wells, bore holes with auger, and one ...
Huang Ying   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Anomaly Detection of Acoustic Signals in Ultra-High Voltage Converter Valves Based on the FAVAE-AS

open access: yesSensors
The converter valve is the core component of the ultra-high voltage direct current (UHVDC) transmission system, and its fault detection is very important to ensure the safe and stable operation of the transmission system.
Shuyan Pan   +4 more
doaj   +1 more source

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