Results 91 to 100 of about 1,722,338 (297)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Weak lensing calibration of mass bias in the REFLEX+BCS X-ray galaxy cluster catalogue

open access: yes, 2017
The use of large, X-ray selected galaxy cluster catalogues for cosmological analyses requires a thorough understanding of the X-ray mass estimates. Weak gravitational lensing is an ideal method to shed light on such issues, due to its insensitivity to ...
Battaglia, Nicholas   +3 more
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Design of a weak bioelectric signal acquisition circuit

open access: yesJournal of Measurement Science and Instrumentation, 2021
A surface electromyography(sEMG) signal acquisition circuit based on high-order filtering is designed. We use a two-stage adjustable amplifier and a high-order Sallen-Key bandpass filter to solve the problems of non-adjustable amplification gain and low ...
ZHOU Mingjuan, WANG Yuyuan, RAN Li
doaj  

CMB lensing reconstruction with point source masks

open access: yes, 2011
An incomplete sky coverage poses difficulties in the extraction of the weak lensing information from the CMB. We test the reconstruction of the weak lensing convergence from CMB maps to which masks of point sources have been applied. We use the quadratic
Carvalho, C. Sofia, Tereno, Ismael
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Robust LHC Higgs Search in Weak Boson Fusion

open access: yes, 2003
We demonstrate that an LHC Higgs search in weak boson fusion production with subsequent decay to weak boson pairs is robust against extensions of the Standard Model or MSSM involving a large number of Higgs doublets. We also show that the transverse mass
Alexandre Alves   +32 more
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Method for assisted-GPS positioning based on ambiguity resolution in weak signal environment

open access: yesTongxin xuebao, 2009
An assisted-GPS positioning algorithm was proposed.Based on this algorithm, the receiver needn’t accomplish the bit synchronization, frame synchronization and navigation data demodulation, which were usually necessary for the conventional GPS receiver ...
SONG Cheng   +2 more
doaj  

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