Results 51 to 60 of about 1,709,745 (295)

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Detection of ultra-weak magnetic fields in Am stars: beta UMa and theta Leo

, 2016
An extremely weak circularly polarized signature was recently discovered in spectral lines of the chemically peculiar Am star Sirius A. A weak surface magnetic field was proposed to account for the observed polarized signal, but the shape of the phase ...
Ariste, A. Lopez, Aurière, M., ballot, J., Blazère, A., Böhm, T., Folsom, C. P., Gaurat, M., Jouve, L., Lignières, F., Neiner, C., Petit, P., Wade, G. A.   +11 more
core   +3 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Neural-Based Nonlinear Device Models for Intermodulation Analysis [PDF]

, 2003
A new procedure to learn a nonlinear model together with its derivative parameters using a composite neural network is presented.So far neural networks have never been used to extract large-signal device model accounting for distortion parameters ...
Colantonio, P., Giannini, F., Leuzzi, G., Orengo, G., Serino, A.   +4 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Optomechanical scheme for the detection of weak impulsive forces [PDF]

, 2001
We show that a cooling scheme and an appropriate quantum nonstationary strategy can be used to improve the signal to noise ratio for the optomechanical detection of weak impulsive forces.Comment: 4 pages, Revtex, 1 ...
A.N. Cleland, C.K. Law, C.M. Caves, C.W. Gardiner, D. F. Walls, David Vitali, H.M. Wiseman, H.M. Wiseman, I. Tittonen, J. Mertz, J.M.W. Milatz, M. Pinard, P.F. Cohadon, Paolo Tombesi, R. Loudon, S. Mancini, S. van der Meer, Stefano Mancini, T.D. Stowe, V. Giovannetti, V. Giovannetti, V.B. Braginsky, Y. Hadjar   +22 more
core   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Identification of Potential Collective Actions Using Enhanced Gray System Theory on Social Media

IEEE Access, 2016
A collective action that considerably affects government management and public security, e.g., a mass demonstration, usually experiences a long development period, originating from small and uncertain variations called weak signals on social media ...
Wei Yang, Xiaohui Cui, Jin Liu, Yancheng Liu   +3 more
doaj   +1 more source

Weak magnetic anomaly signal detection based on the entropy of mixed differential signal

AIP Advances, 2021
Magnetic anomaly detection is of great significance in geological exploration and underwater target detection. However, the magnetic anomaly signal is not easy to be detected because of its weakness relative to the magnetic environmental noise, and the ...
Z. Wang, J. Qiu, D. Xie, J. Ou, Q. Xu
doaj   +1 more source