Results 91 to 100 of about 860,460 (345)

Collection of remote optical signals by air waveguides

, 2014
Collection of weak signals from remote locations is the primary goal and the primary hurdle of optical stand-off detection schemes. Typically, the measured signal is enhanced using large numerical aperture collection optics and high gain detectors.
Jhajj, N., Milchberg, H. M., Rosenthal, E. W., Wahlstrand, J. K.   +3 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Chaotic Effect-Based Array Duffing Systems with Improved Nonlinear Restoring Force for Weak Signal Detection in Dynamic MWD. [PDF]

Sensors (Basel), 2023
Yang Y, Ding Q, Gao Y, Chen J.
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Research on an Echo-Signal-Detection Algorithm for Weak and Small Targets Based on GM-APD Remote Active Single-Photon Technology

Photonics
Geiger-mode avalanche photodiode (GM-APD) is a single-photon-detection device characterized by high sensitivity and fast response, which enables it to detect echo signals of distant targets effectively.
Shengwen Yin, Sining Li, Xin Zhou, Jianfeng Sun, Dongfang Guo, Jie Lu, Hong Zhao   +6 more
doaj   +1 more source

An ultrahigh sensitivity acoustic sensor system for weak signal detection based on an ultrahigh-Q CaF₂ resonator. [PDF]

Microsyst Nanoeng, 2023
Xing T, Xing E, Jia T, Li J, Rong J, Li L, Tian S, Zhou Y, Liu W, Tang J, Liu J.   +10 more
europepmc   +1 more source

Testing Weak Lensing Maps With Redshift Surveys: A Subaru Field

, 2012
We use a dense redshift survey in the foreground of the Subaru GTO2deg^2 weak lensing field (centered at $\alpha_{2000}$ = 16$^h04^m44^s$;$\delta_{2000}$ =43^\circ11^{\prime}24^{\prime\prime}$) to assess the completeness and comment on the purity of ...
Adelman-McCarthy, Casertano, Daniel G. Fabricant, Dressler, Geller, Geller, Girardi, Hamana, Hennawi, Hoekstra, Ian P. Dell’Antonio, Khiabanian, Koester, Kubo, Leauthaud, Lubin, Lubin, Lubin, Margaret J. Geller, Michael J. Kurtz, Mink, Miyazaki, Miyazaki, Mobasher, Postman, Rines, Rines, Satoshi Miyazaki, Shan, Spergel, Struble, Taniguchi, White, Wittman, Wittman, Yousuke Utsumi   +35 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source