Results 81 to 90 of about 861,138 (294)

Effects of Second-Order Matched Stochastic Resonance for Weak Signal Detection

IEEE Access, 2018
Weak signal detection via stochastic resonance (SR) has attracted considerable attention in a wide range of research fields, especially under heavy background noise circumstances.
Haitao Dong, Haiyan Wang, Xiaohong Shen, Zhe Jiang   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Weak Coherent Light Interference Heterodyne Detection Based on Time-Domain Signal Analysis

IET Signal Processing
Weak coherent light interference heterodyne detection is the theoretical basis for fiber optic gyroscopes, optical coherence tomography, and optical time-domain reflectometers.
Hui Shen, Yousen Li
doaj   +1 more source

Weak GPS Signal Acquisition Algorithm Based on Chaotic Oscillator

EURASIP Journal on Advances in Signal Processing, 2009
To detect weak Global Position System (GPS) signal indoors, various high-sensitivity detection algorithms have been proposed. However, a common tradeoff between high-sensitivity and computation burden impedes development of high sensitivity GPS receiver.
Zhiqin Zhao, Yiming Pi, Pengda Huang
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Algorithm Used to Detect Weak Signals Covered by Noise in PIND

International Journal of Aerospace Engineering, 2019
Detection of the loose particles is urgently required in the spacecraft production processes. PIND (particle impact noise detection) is the most commonly used method for the detection of loose particles in the aerospace electronic components.
G. T. Wang, X. W. Liang, Y. Y. Xue, C. Li, Q. Ding   +4 more
doaj   +1 more source

Study on a New Electromagnetic Flow Measurement Technology Based on Differential Correlation Detection

Sensors, 2020
Under the conditions of low flow rate and strong noise, the current electromagnetic flowmeter (EMF) cannot satisfy the requirement for measurement or separate the actual flow signal and interference signal accurately. Correlation detection technology can
Liang Ge, Junxian Chen, Guiyun Tian, Wen Zeng, Qi Huang, Ze Hu   +5 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source