Results 91 to 100 of about 861,138 (294)

Chaotic Effect-Based Array Duffing Systems with Improved Nonlinear Restoring Force for Weak Signal Detection in Dynamic MWD. [PDF]

Sensors (Basel), 2023
Yang Y, Ding Q, Gao Y, Chen J.
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

An ultrahigh sensitivity acoustic sensor system for weak signal detection based on an ultrahigh-Q CaF₂ resonator. [PDF]

Microsyst Nanoeng, 2023
Xing T, Xing E, Jia T, Li J, Rong J, Li L, Tian S, Zhou Y, Liu W, Tang J, Liu J.   +10 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Research on an Echo-Signal-Detection Algorithm for Weak and Small Targets Based on GM-APD Remote Active Single-Photon Technology

Photonics
Geiger-mode avalanche photodiode (GM-APD) is a single-photon-detection device characterized by high sensitivity and fast response, which enables it to detect echo signals of distant targets effectively.
Shengwen Yin, Sining Li, Xin Zhou, Jianfeng Sun, Dongfang Guo, Jie Lu, Hong Zhao   +6 more
doaj   +1 more source

Can the Gravitational Wave Background from Inflation be Detected Locally?

, 1993
The Cosmic Background Explorer (COBE) detection of microwave background anisotropies may contain a component due to gravitational waves generated by inflation.
A. D. Linde, A. D. Linde, A. D. Linde, A. D. Linde, A. H. Guth, A. R. Liddle, A. R. Liddle, A. R. Liddle, Andrew R. Liddle, B. Allen, D. La, D. S. Salopek, D. S. Salopek, E. W. Kolb, F. Lucchin, F. Lucchin, G. F. Smoot, J. D. Barrow, J. E. Lidsey, J. E. Lidsey, K. Freese, K. S. Thorne, L. F. Abbott, L. M. Krauss, L. P. Grishchuk, M. S. Turner, M. White, N. Christensen, R. Crittenden, R. L. Davis, R. L. Davis, T. Souradeep, V. Sahni   +32 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Обнаружение слабых периодических сигналов с использованием модифицированной системы Дуффинга-Холмса дробного порядка [PDF]

, 2013
У роботі запропонована модифікована система Дуффінга-Холмса дробового порядку, призначена для виявлення слабких періодичних сигналів. Розроблена модель дозволяє знизити мінімальний поріг виявлення періодичного сигналу модифікованою системою Дуффінга ...
Fedula, M., Martynyuk, V., Мартинюк, В.В., Мартынюк, В.В., Федула, М.В., Федула, Н.В.   +5 more
core  

An ultra-sensitive pulsed balanced homodyne detector: Application to time-domain quantum measurements

, 2001
A pulsed balanced homodyne detector has been developed for precise measurements of electric field quadratures of pulsed optical quantum states. A high level of common mode suppression (> 85 dB) and low electronic noise (730 electrons per pulse) provide a
A. I. Lvovsky, Anderson, Breitenbach, C. Hettich, Daly, D’Ariano, Foster, Furusawa, H. Hansen, Hirano, J. Mlynek, Lam, Lvovsky, Ou, P. Lodahl, S. Schiller, Schneider, Slusher, Smithey, Smithey, T. Aichele, Vasilyev, Wu, Yuen   +23 more
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source