Results 71 to 80 of about 1,205,866 (291)
Megatrends and weak signals shaping future real estate
Buildings & CitiesSociety prepares for an envisioned future by shaping that future to align with current perceptions. This paper explores real estate market participants’ (n ≥ 840) perceptions of various forces influencing the future of housing, retail and office spaces ...
Saija Toivonen
doaj +1 more source
The test case of HD26965: difficulties disentangling weak Doppler signals from stellar activity
, 2018 We report the discovery of a radial velocity signal that can be interpreted as a planetary-mass candidate orbiting the K dwarf HD26965, with an orbital period of 42.364$\pm$0.015 days, or alternatively, as the presence of residual, uncorrected rotational
Arriagada, Pamela +11 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Weak Signal Enhance Based on the Neural Network Assisted Empirical Mode Decomposition
Sensors, 2020 In order to enhance weak signals in strong noise background, a weak signal enhancement method based on EMDNN (neural network-assisted empirical mode decomposition) is proposed.
Kai Chen +3 more
doaj +1 more source
Share buy-backs in Germany overreaction to weak signals? : [Version April 2004] [PDF]
, 2004 This paper investigates the magnitude and the main determinants of share price reactions to buy-back announcements of German corporations. For our comprehensive sample of 224 announcements that took place between May 1998 and April 2003 we find average ...
Hackethal, Andreas +1 more
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Quantum lock-in measurement of weak alternating signals
Quantum FrontiersThe detection of weak time-dependent alternating signals in a strongly noisy background is an important problem in physics and a critical task in metrology. Quantum lock-in amplifier can extract alternating signals within extreme noises by using suitable
Min Zhuang +3 more
doaj +1 more source
Weak positive cloud-to-ground flashes in Northeastern Colorado [PDF]
The frequency distributions of the peak magnetic field associated with the first detected return stroke of positive and negative cloud-to-ground (CG) flashes were studied using lightning data from northeastern Colorado.
Garcia-Miguel, Juan A. +3 more
core +1 more source