Results 91 to 100 of about 971,014 (304)
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
MathematicsThis paper systematically studies a class of weakly singular Wendroff-type integral inequalities with multiple variables and multiple nonlinear terms.
Yongsheng Li, Zizun Li
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Gravitational collapse in Rastall gravity
Physics Letters B, 2019 We study spherically symmetric gravitational collapse of a homogeneous perfect fluid in Rastall gravity. Considering a linear equation of state (EoS) for the fluid profiles, we examine the conditions under which the collapse scenario could end in a ...
A. H. Ziaie, H. Moradpour, S. Ghaffari
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Nonlocal Changing-Sign Perturbation Tempered Fractional Sub-Diffusion Model with Weak Singularity
Fractal and FractionalIn this paper, we study the existence of positive solutions for a changing-sign perturbation tempered fractional model with weak singularity which arises from the sub-diffusion study of anomalous diffusion in Brownian motion. By two-step substitution, we
Xinguang Zhang +4 more
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
A non-static quantum inspired spacetime in f(R) gravity: Gravity's rainbow
Nuclear Physics B, 2020 In this note we explore a non-static spacetime in quantum regime in the background of f(R) gravity. The time dependent Vaidya metric which represents the spacetime of a radiating body like star is studied in an energy dependent gravity's rainbow, which ...
Prabir Rudra
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ON COMPACTNESS OF WEAK SQUARE AT SINGULARS OF UNCOUNTABLE COFINALITY
The Journal of Symbolic LogicAbstract Cummings, Foreman, and Magidor proved that Jensen’s square principle is non-compact at $\aleph _\omega $ , meaning that it is consistent that
openaire +4 more sources
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Existence of periodic solutions of a Liénard equation with a singularity of repulsive type
Boundary Value Problems, 2017 In this paper, the problem of positive periodic solutions is studied for the Liénard equation with a singularity of repulsive type, x ″ + f ( x ) x ′ − α ( t ) x μ = h ( t ) , $$ x''+f(x)x'-\frac{\alpha(t)}{x^{\mu}}=h(t), $$ where f : ( 0 , + ∞ ) → R $f:(
Shiping Lu, Yajiao Wang, Yuanzhi Guo
doaj +1 more source