Results 71 to 80 of about 971,014 (304)

sylabs/singularity: SingularityCE 3.9.7

, 2022
SingularityCE 3.9.7 is a bugfix release, with the following changes: Bug fixes Support nvidia-container-cli v1.8.0 and above, via fix to capability set. Avoid cleanup panic when invalid file specified for --apply-cgroups. Thanks / Reporting Bugs Thanks
cclerget, Dave Trudgian, Ian Kaneshiro, David Godlove, Michael Bauer, Gregory M. Kurtzer   +5 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Gravitational Collapse and Singularity Removal in Rastall Theory

Advances in High Energy Physics, 2021
In the present work, we study spherically symmetric gravitational collapse of a homogeneous fluid in the framework of Rastall gravity. Considering a nonlinear equation of state (EoS) for the fluid profiles, we search for a class of nonsingular collapse ...
Ehsan Dorrani
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Null weak singularities in plane-symmetric space-times [PDF]

Physical Review D, 1998
We construct a new class of plane-symmetric solutions possessing a curvature singularity which is null and weak, like the spacetime singularity at the Cauchy horizon of spinning (or charged) black holes. We then analyse the stability of this singularity using a rigorous non-perturbative method.
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A Fast Finite Difference Method for 2D Time Fractional Mobile/Immobile Equation with Weakly Singular Solution

Fractal and Fractional
This paper presents a fast Crank–Nicolson L1 finite difference scheme for the two-dimensional time fractional mobile/immobile diffusion equation with weakly singular solution at the initial moment.
Haili Qiao, Aijie Cheng
doaj   +1 more source

singularityware/singularity: Singularity 2.6.0 Release Candidate 1

, 2018
<p>Greetings Singularity-ers!</p> <p>I'm excited to announce the second release candidate for the 2.6 branch! This release candidate has a bug fix and lot of cool new features.</p> <p>Please test it in your environments when
George Hartzell, David Godlove, Justin Riley, Felix Abecassis, Amanda Duffy, Richard Neuboeck, Carl Madison, crbaird, Gregory M. Kurtzer, Daniele Tamino, yhcote, Oliver Freyermuth, cclerget, tri-adam, DrDaveD, Michael Bauer, Jason Stover, Brian Bockelman, Dexter, Tru Huynh, Mark Egan-Fuller, wpoely86, Vanessa Sochat, Yaroslav Halchenko, Satrajit Ghosh, Eduardo Arango, David Trudgian, Dave Love, DERNAT Rémy, Maciej Sieczka   +29 more
core   +1 more source

sylabs/singularity: SingularityCE 3.9.1

, 2021
This is a security release for SingularityCE 3.9, addressing a security issue in SingularityCE's dependencies. Security Related Fixes CVE-2021-41190 / GHSA-77vh-xpmg-72qh: OCI specifications allow ambiguous documents that contain both "manifests" and ...
Dave Trudgian, David Godlove, Felix Abecassis, Carl Madison, Amanda Duffy, Mike Frisch, Gregory M. Kurtzer, Brian P Bockelman, Daniele Tamino, Justin Cook, Jacob Chappell, cclerget, Geoffroy Vallee, DrDaveD, Michael Bauer, Jason Stover, Adam Hughes, Tru Huynh, Mike Gray, Sasha Yakovtseva, Marcelo Magallon, Yannick Cote, Ian Kaneshiro, Yaroslav Halchenko, Satrajit Ghosh, Vanessasaurus, Carlos Eduardo Arango Gutierrez, VP   +27 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source