Results 151 to 160 of about 5,114,170 (301)

Generalized Weak Solutions

, 2021
Eduard Feireisl, Mária Lukáčová-Medviďová, Hana Mizerová, Bangwei She   +3 more
openaire   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

On weak-strong uniqueness property for full compressible magnetohydrodynamics flows

Open Mathematics, 2013
Yan Weiping
doaj   +1 more source

The decomposition of a solution of the quasilinear stochastic parabolic equation with weak source

, 2007
We obtain conditions which guarantee the existence of a decomposition of a solution of the quasilinear stochastic parabolic equation with a weak ...
Melnik, S.
core  

Improved Moduli of Continuity for Degenerate Phase Transitions. [PDF]

Ann PDE
Gianazza U, Liao N, Urbano JM.
europepmc   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Conservation laws. II: Weak solutions

, 2007
Summary: For parts I and III see [ibid. 81--90 (2007; Zbl 1156.35428)] and ibid. 107--115 (2007; Zbl 1156.35425)]. We apply the maximum principle and the compensated compactness method to get the existence of weak solutions to the Cauchy problems for the nonlinear hyperbolic conservation laws of quadratic flux and the LeRoux system with sources.
TAO, MING, CHENG, ZHIXIN, YAN, JIN
openaire   +2 more sources

Combined Nav1.7-Nav1.8 channel abrogation: Supralinear suppression of excitability in a subpopulation of peripheral sensory neurons. [PDF]

J Gen Physiol
Vasylyev D, Tyagi S, Ghovanloo MR, Zhao P, Waxman SG.   +4 more
europepmc   +1 more source