Results 141 to 150 of about 11,044,020 (324)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Generalized quasi-linear fractional Wentzell problems

Advances in Nonlinear Analysis
Given a bounded (ε,δ)\left(\varepsilon ,\delta )-domain Ω⊆RN\Omega \subseteq {{\mathbb{R}}}^{N} (N≥2N\ge 2) whose boundary Γ≔∂Ω\Gamma := \partial \Omega is a dd-set for d∈(N−p,N)d\in \left(N-p,N), we investigate a generalized quasi-linear elliptic ...
Mesino-Espinosa Efren, Vélez-Santiago Alejandro   +1 more
doaj   +1 more source

Solutions of the attraction-repulsion-chemotaxis system with nonlinear diffusion

Mathematical Modelling and Analysis
In this study, we consider the well-posedness of the attraction-repulsion chemotaxis system. This paper explores the dynamics of species movement in reaction to two chemically opposing substances, incorporating nonlinear diffusion. Our primary objective
Yadhavan Karuppusamy, Shangerganesh Lingeshwaran   +1 more
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Study of weak solutions for parabolic variational inequalities with nonstandard growth conditions. [PDF]

J Inequal Appl, 2018
Dong Y.
europepmc   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Existence of solutions for quasilinear elliptic degenerate systems with L^1 data and nonlinearity in the gradient

Electronic Journal of Differential Equations, 2013
In this article we show the existence of weak solutions for some quasilinear degenerate elliptic systems arising in modeling chemotaxis and angiogenesis.
Abdelhaq Mouida, Noureddine Alaa, Salim Mesbahi, Walid Bouarifi   +3 more
doaj  

Optimal partial regularity of very weak solutions to nonhomogeneous A-harmonic systems. [PDF]

J Inequal Appl, 2017
Zhao Q, Chen S.
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Infinitely many weak solutions of the p-Laplacian equation with nonlinear boundary conditions. [PDF]

ScientificWorldJournal, 2014
Lu FY, Deng GQ.
europepmc   +1 more source