Results 41 to 50 of about 3,919,417 (298)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

The regularity of weak solutions for certain n-dimensional strongly coupled parabolic systems

open access: yesAdvanced Nonlinear Studies, 2022
This paper is concerned with the n-dimensional strongly coupled parabolic systems with triangular form in the cylinder Ω×(0,T]\Omega \times (0,T]. We investigate L2{L}^{2} and Hölder regularity of the derivatives of weak solutions (u1,u2)\left({u}_{1},{u}
Tan Qi-Jian
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

On Weak Solutions of Highly Degenerate SDEs

open access: yesAutomation and Remote Control, 2020
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +4 more sources

Weak-strong uniqueness for measure-valued solutions to the equations of quasiconvex adiabatic thermoelasticity

open access: yes, 2022
This article studies the equations of adiabatic thermoelasticity endowed with an internal energy satisfying an appropriate quasiconvexity assumption which is associated to the symmetrisability condition for the system.
Andreas Panagiotis Vikelis (6268091)   +2 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

On global weak solutions of the Vlasov-Poisson equations with external magnetic field

open access: yesСовременная математика: Фундаментальные направления, 2023
We consider the first mixed problem for the system of Vlasov-Poisson equations with a given external magnetic field in a bounded domain. This problem describes the kinetics of high-temperature plasma in controlled thermonuclear fusion plants and is ...
Yu. O. Belyaeva, A. L. Skubachevskii
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

RELATIONSHIP BETWEEN WEAK ENTWINING STRUCTURES AND WEAK CORINGS [PDF]

open access: yes, 2010
Given a commutative ring with unit, -algebra and -coalgebra Triple is called (weak) entwining structure if there is -linear map that fulfil some axioms.
Puspita, Nikken Prima
core   +1 more source

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