Results 81 to 90 of about 1,612,054 (235)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

CoDA: A Cognitive-Inspired Approach for Domain Adaptation

Applied Sciences
Modern neural networks have achieved remarkable success in visual recognition; however, due to their sensitivity to domain shifts, Unsupervised Domain Adaptation (UDA) remains an open research problem.
Cavide Balkı Gemirter, Emin Erkan Korkmaz, Dionysis Goularas   +2 more
doaj   +1 more source

Meibomian glands segmentation in infrared images with limited annotation [PDF]

International Journal of Ophthalmology
AIM: To investigate a pioneering framework for the segmentation of meibomian glands (MGs), using limited annotations to reduce the workload on ophthalmologists and enhance the efficiency of clinical diagnosis.
Jia-Wen Lin, Ling-Jie Lin, Feng Lu, Tai-Chen Lai, Jing Zou, Lin-Ling Guo, Zhi-Ming Lin, Li Li   +7 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Zero-Shot Annotation by Large Language Model with Serial Correction of Mixed Label Corruption for Weakly Supervised Financial News Classification

Information
Multi-label classification of financial news is frequently affected by incomplete and noisy annotations, while obtaining expert-curated labels at scale is prohibitively expensive.
Jianxin Sun, Haichuan Liu
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

PCA-Guided Weakly Supervised Mapping of Hydroxyl- and Iron-Oxide-Related Spectral Anomalies Using Landsat 8 OLI

Sensors
Interpreting multispectral remote sensing data for hydrothermal alteration mapping remains challenging in complex mountainous metallogenic belts because dense pixel-level field labels are difficult to obtain and weak spectral responses are affected by ...
Kaikai Pang, Yaxiaer Yalikun, Bowen Zhang, Fei Ling, Yilihamujiang Tuniyazi   +4 more
doaj   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Learning Object Detection with Weak Supervision [PDF]

, 2023
University of Technology Sydney. Faculty of Engineering and Information Technology.Deep learning technique has achieved astonishing success in many computer vision applications.
Xu, Yunqiu
core   +1 more source

Global Detection and Morphological Characterization of Seamounts With Weakly Supervised Deep Learning

Journal of Geophysical Research: Machine Learning and Computation
Seamounts are submarine volcanic features that record the tectonic and magmatic evolution of Earth's interior, yet their global distribution remains poorly resolved due to sparse high‐resolution bathymetric coverage.
Zhengfa Bi, Xinming Wu, Xiaohua Xu, Nori Nakata   +3 more
doaj   +1 more source