Results 31 to 40 of about 1,601,375 (284)

Coincidence Points and Common Fixed Points of Cyclic Maps by Implicit Contractive Conditions

مجلة بغداد للعلوم
The study of common fixed points and coincidence points has occupied a large part of the priorities of researchers, especially in the metric space and its generalizations.
Abbas Karim Nahi, Salwa Salman Abed
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Weak contractive integral inequalities and fixed points in modular metric spaces

Journal of Inequalities and Applications, 2016
Branciari (Int. J. Math. Math. Sci. 29(9):531-536, 2002) gave an interesting supplement of Banach’s contraction principle for an integral-type inequality.
Nawab Hussain, Marwan A Kutbi, Nazra Sultana, Iram Iqbal   +3 more
doaj   +1 more source

Common fixed point for two weakly compatible pairs of self-maps through property E. A. under an implicit relation [PDF]

, 2012
We prove some generalizations of the results of Renu Chug-Sanjay Kumar, the author with necessary corrections, and of Rhoades et al. for weakly compatible self-maps satisfying the property E. A. under an implicit relation.
Phaneendra, T., Swatmaram, Swatmaram
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

GENERAL FIXED POINT THEOREMS FOR WEAKLY COMPATIBLE MAPS

Demonstratio Mathematica, 2005
Summary: The purpose of this note is to use general expansive and conditions minimal type commutativity without continuity requirements to prove some fixed point theorems. The theorems extend known results from the class of compatible continuous expansive maps to a wider class of mappings.
openaire   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Common Fixed Point Theorems for Weakly Compatible Mappings

Rocky Mountain Journal of Mathematics, 2003
Let \((X,d)\) be a metric space, \(F\), \(G: X \multimap X\) be set-valued mappings and \(I\), \(J:X\to X\) two mappings. The author gives metric conditions which imply that there exists \(x \in X\) such that \(F(x)=G(x)=\{x\}\) and \(I(x)=J(x)=x\).
openaire   +3 more sources