Results 231 to 240 of about 26,626 (276)

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

open access: yesAdvanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann   +15 more
wiley   +1 more source

Mitogenomics of Central American weakly-electric fishes

Gene, 2019
Electric fishes are a diverse group of freshwater organisms with the ability to generate electric organ discharges (EODs) that are used for communication and electrolocation. This group (ca. 200 species) has originated in South America, and six species colonized the Central American Isthmus.
Celestino Aguilar   +4 more
openaire   +2 more sources

Oxygen consumption in weakly electric Neotropical fishes

Oecologia, 2003
Weakly electric gymnotiform fishes with wave-type electric organ discharge (EOD) are less hypoxia-tolerant and are less likely to be found in hypoxic habitats than weakly electric gymnotiforms with pulse-type EOD, suggesting that differences in metabolism resulting from EOD type affects habitat choice.
David, Julian   +3 more
openaire   +2 more sources

Peripheral electrosensory imaging by weakly electric fish

Journal of Comparative Physiology A, 2006
Different species have developed different solutions to the problem of constructing a representation of the environment from sensory images projected onto sensory surfaces. Comprehension of how these images are formed is an essential first step in understanding the representation of external reality by a given sensory system. Modeling of the electrical
A A, Caputi, R, Budelli
openaire   +2 more sources

Weakly electric fish for biomonitoring water quality

Environmental Technology, 2012
Environmental pollution is a major issue that calls for suitable monitoring systems. The number of possible pollutants of municipal and industrial water grows annually as new chemicals are developed. Technical devices for pollutant detection are constructed in a way to detect a specific and known array of pollutants.
Juergen, Clausen   +2 more
openaire   +2 more sources

Electrical sensitivity of a weakly electric fish

Life Sciences, 1967
Abstract The South American gymnotid, Sternarchus albifrons produces a weak electric field of high frequency (600–1000 Hz) by means of a caudal electric organ (1,2). Electroreceptor organs have been found in the skin, innervated by the lateral line nerve (2,3). Electrical sensing by several other gymnotids has been studied (2,4–6).
Louis P. Granath   +2 more
openaire   +1 more source

The bioinspiring potential of weakly electric fish

Bioinspiration & Biomimetics, 2017
Electric fish are privileged animals for bio-inspiring man-built autonomous systems since they have a multimodal sense that allows underwater navigation, object classification and intraspecific communication. Although there are taxon dependent variations adapted to different environments, this multimodal system can be schematically described as having ...
openaire   +2 more sources

Cyclic AMP modulates electrical signaling in a weakly electric fish

Journal of Comparative Physiology A, 2003
Many species of electric fish show diurnal or socially elicited variation in electric organ discharge amplitude. In Sternopygus macrurus, activation of protein kinase A by 8-bromo-cAMP increases electrocyte sodium current magnitude. To determine whether the behavioral plasticity in electric organ discharge amplitude is controlled by electrocyte ...
L, McAnelly, A, Silva, H H, Zakon
openaire   +2 more sources

Species recognition in mormyrid weakly electric fish

Animal Behaviour, 1986
Abstract We investigated group cohesion in four species of African weakly electric fish (Brienomyrus niger, Gnathonemus petersii, Marcusenius cyprinoides and Pollimyrus isidori). The attraction among members of the same and different species served as the criterion for species recognition.
Peter Moller, Jacques Serrier
openaire   +1 more source

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