Results 121 to 130 of about 1,686 (292)

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Gellan Gum Fluid Gel System for Controlled‐Delivery of Cytokine‐Licensed MSC‐EVs to Enhance Corneal Repair in Limbal Stem Cell Deficiency

Advanced Healthcare Materials, EarlyView.
Gellan gum fluid gel (FG) enables controlled ocular delivery of mesenchymal stromal cell (MSC)‐derived extracellular vesicles (EV). Its shear‐thinning, solid‐liquid‐solid rheology ensures prolonged ocular retention. Sustained MSC‐EV release (∼18% in 6 hrs) supports effective EV ocular delivery.
Seyedmohammad Moosavizadeh, Ava Dashti, Thomas E. Robinson, Robyn Gaffey, Richard Moakes, Neil Lagali, Liam Grover, Thomas Ritter   +7 more
wiley   +1 more source

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

On the rate of convergence of projection-iterative methods for classes of weakly singular integral equations [PDF]

, 1995
Для класів слабо-сингулярних інтегральних рівнянь II роду, ядра яких мають степеневу особливість, знайдено оптимальний порядок швидкості збіжності проекційно-ітеративних методів. Крім того, розглянуто ітераційні методи типу метода Ю. Д.
Аскаров, М., Переверзев, С.В.   +1 more
core   +2 more sources

Reproducing kernel method for a class of weakly singular Fredholm integral equations

Journal of Taibah University for Science, 2018
Numerical methods for solving integral equations have been the focus of much research, including reproducing kernel methods. We present a new algorithm to solve weakly singular Fredholm integral equations (WSFIEs). The advantage of this method is that it
Azizallah Alvandi, Mahmoud Paripour
doaj   +1 more source

Rational Design of Organic Chromophores for Simultaneously Trig‐gering Redox Imbalance and Tracking Organelles in Biological Sys‐tems Under Near‐Infrared Light Irradiation

Advanced Healthcare Materials, EarlyView.
TOC represents the synthesis of theory‐guided novel near‐infrared (NIR) light‐absorbing organic photosensitizers (OPS) enabling redox‐induced tumor phototherapy and single‐cell organelle tracking. ABSTRACT The design of organic photosensitizers that operate efficiently in the near‐infrared (NIR) region remains challenging due to the need to balance ...
Pragti, Bidyut Kumar Kundu, Jiajie Diao, Yujie Sun   +3 more
wiley   +1 more source

Solvability of m-product mixed non-linear functional integral equations

Beni-Suef University Journal of Basic and Applied Sciences
The purpose of this paper is devoted to establishing the existence of solutions for m-product non-linear functional integral equations with weakly singular and Riemann–Liouville integral terms.
Amar Deep, Manochehr Kazemi, Mohammad Ali Fariborzi Araghi, Mohammad Esmael Samei   +3 more
doaj   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

Advanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong, You Zhou, Qingxiu Li, Wenyu Zhao, Sunyingyue Geng, Hangfei Li, Yan‐Bing Leng, Shirui Zhu, Guanglong Ding, Yongbiao Zhai, Ziyu Lv, Ye Zhou, Su‐Ting Han   +12 more
wiley   +1 more source

Convergence of adaptive 3D BEM for weakly singular integral equations based on isotropic mesh-refinement [PDF]

, 2013
We consider the adaptive lowest-order boundary element method (ABEM) based on isotropic mesh-refinement for the weakly-singular integral equation for the 3D Laplacian. The proposed scheme resolves both, possible singularities of the solution as well as
Karkulik, Michael, Praetorius, Dirk, Of, Günther   +2 more
core  

Convergence Analysis of the Tau Method for Volterra–Fredholm Integrodifferential Equations With Weakly Singular Kernel

Journal of Applied Mathematics
This work focuses on the analysis of the Volterra–Fredholm integral equation (VFIE) with a weakly singular kernel, which is a transformed form of a partial integrodifferential equation (PIDE) with a weakly singular kernel. We present an approach based on
Javad Shokri, Saeed Pishbin, Ahmed M. Rajab   +2 more
doaj   +1 more source