Results 91 to 100 of about 539,870 (246)

A weakly-supervised follicle segmentation method in ultrasound images

Scientific Reports
Accurate follicle segmentation in ultrasound images is crucial for monitoring follicle development, a key factor in fertility treatments. However, obtaining pixel-level annotations for fully supervised instance segmentation is often impractical due to ...
Guanyu Liu, Weihong Huang, Yanping Li, Qiong Zhang, Jing Fu, Hongying Tang, Jia Huang, Zhongteng Zhang, Lei Zhang, Yu Wang, Jianzhong Hu   +10 more
doaj   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans

FEBS Open Bio, EarlyView.
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller, Jana Bleher, Birgit Weinberger, Lourdes Rocamora‐Reverte   +3 more
wiley   +1 more source

Field-based estimation of cotton seedling agronomic traits: Using UAV-LiDAR and weakly supervised semantic segmentation

Industrial Crops and Products
Accurate estimation of the cotton seedling Leaf Area Index (LAI) is essential for yield prediction and precision crop management. Traditional manual methods are limited by low throughput, while two-dimensional remote sensing techniques often struggle ...
Zhendong Zhang, Sheng Wen, Lei Zhang, Jiehong Wu, Fagang Liu, Zhiyin Deng, Sipei Li   +6 more
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

An One-step Triple Enhanced weakly supervised semantic segmentation using image-level labels.

PLoS ONE
Weakly supervised semantic segmentation, based on image-level labels, abandons the pixel-level labels relied upon by traditional semantic segmentation algorithms.
Longjie Quan, Dandan Huang, Zhi Liu, Kai Gao, Xiaohong Mi   +4 more
doaj   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Competing for Pixels: A Self-Play Algorithm for Weakly-Supervised Semantic Segmentation

Weakly-supervised semantic segmentation (WSSS) methods, reliant on image-level labels indicating object presence, lack explicit correspondence between labels and regions of interest (ROIs), posing a significant challenge.
João Ramalhinho, Iani J.M.B. Gayo, Shiqi Huang, Matthew J. Clarkson, Ester Bonmati, Stephen P. Pereira, Yipeng Hu, Shaheer U. Saeed, Nina Montaña-Brown, Brian Davidson, Dean C. Barratt   +10 more
core   +1 more source