Results 71 to 80 of about 539,870 (246)
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
WSF-NET: Weakly Supervised Feature-Fusion Network for Binary Segmentation in Remote Sensing Image
Remote Sensing, 2018 Binary segmentation in remote sensing aims to obtain binary prediction mask classifying each pixel in the given image. Deep learning methods have shown outstanding performance in this task.
Kun Fu +6 more
doaj +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
IEEE AccessClass Activation Mapping (CAM) methods are widely applied in weakly supervised learning tasks due to their ability to highlight object regions. However, conventional CAM methods highlight only the most discriminative regions of the target.
Qingdong Cai, Charith Abhayaratne
doaj +1 more source
Weakly- and semi-supervised panoptic segmentation [PDF]
, 2018 We present a weakly supervised model that jointly performs both semantic- and instance-segmentation – a particularly relevant problem given the substantial cost of obtaining pixel-perfect annotation for these tasks.
Arnab, A +8 more
core +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
IEEE AccessThis study introduces a novel approach to sentiment classification of Arabic tweets regarding educational reforms in Saudi Arabia. The complexity of the Arabic language, with its numerous dialects, poses challenges for natural language processing tasks ...
Alanoud Alotaibi +2 more
doaj +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
WSPolyp-SAM: Weakly Supervised and Self-Guided Fine-Tuning of SAM for Colonoscopy Polyp Segmentation
Applied SciencesEnsuring precise segmentation of colorectal polyps holds critical importance in the early diagnosis and treatment of colorectal cancer. Nevertheless, existing deep learning-based segmentation methods are fully supervised, requiring extensive, precise ...
Tingting Cai +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source