Classification of Alzheimer's Disease Based on Weakly Supervised Learning and Attention Mechanism. [PDF]
Wu X, Gao S, Sun J, Zhang Y, Wang S.
europepmc +1 more source
De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li +23 more
wiley +1 more source
Classification and localization of maize leaf spot disease based on weakly supervised learning. [PDF]
Yang S +10 more
europepmc +1 more source
Weakly Supervised Learning Creates a Fusion of Modeling Cultures
Chengliang Tang, Gan Yuan, Tian Zheng
openalex +1 more source
This work introduces an open‐source all‐optical platform for functional phenotyping of human stem cell‐derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and analysis to resolve single‐cell and network activity, enabling longitudinal measurements, disease modeling, and pharmacological screening in preclinical ...
Wardiya Afshar‐Saber +12 more
wiley +1 more source
Weakly-supervised learning method for the recognition of potato leaf diseases. [PDF]
Chen J +5 more
europepmc +1 more source
A Weakly Supervised Method for Topic Segmentation and Labeling in Goal-oriented Dialogues via Reinforcement Learning [PDF]
Ryuichi Takanobu +6 more
openalex +1 more source
Causal Prediction of TP53 Variant Pathogenicity Using a Perturbation‐Informed Protein Language Model
A TP53‐specific predictor, CaVepP53, is developed by fine‐tuning ESMC on experimentally validated variants, quantifying pathogenicity via Euclidean distances. It outperforms general‐purpose models and extends to five cancer genes, enabling interpretable variant classification for precision medicine.
Huiying Chen +15 more
wiley +1 more source
Coupled Above‐ and Belowground Ecosystem Stability Worldwide
Are the worlds above and below our feet in sync? This global exploration reveals an entangled fate between above‐ and belowground ecosystem stability. It identifies arid regions as hotspots for this coupling and highlights temperature stability as a vital safeguard for maintaining ecosystem balance across our warming planet.
Zexin Meng +18 more
wiley +1 more source
Weakly supervised learning analysis of Aβ plaque distribution in the whole rat brain. [PDF]
Chen Z +7 more
europepmc +1 more source

