Results 131 to 140 of about 458,996 (249)

Clinical features and long-term surgical outcomes of conus medullaris hemangioblastomas. [PDF]

Egypt J Neurosurg
Zhang L, Han B, Jia W.
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Low-Dose Neostigmine at 0.7 Train-of-Four Ratio Safely Accelerates Neuromuscular Recovery: A Prospective Observational Study. [PDF]

Drug Des Devel Ther
Koo CH, Choi CI, Park I, Lee S, Oh AY.
europepmc   +1 more source

Are the Weak Channels Really Weak?

, 2009
The transfer probabilities for 20Ne + 90Zr and 20Ne + 92Zr at energies near the Coulomb barrier were measured. This quantity turned out to be very similar for both Zr isotopes and does not explain the observed differences in the barrier height distributions for these ...
Piasecki, E., Trzcińska, A., Gawlikowicz, W., Jastrzębski, J., Keeley, N., Kisieliński, M., Kliczewski, S., Kordyasz, A., Kowalczyk, M., Khlebnikov, S., Koshchiy, E., Kozulin, E., Krogulski, T., Lotkiev, T., Mutterer, M., Piasecki, K., Piórkowska, Aleksandra, Rusek, K., Staudt, A., Strojek, I., Trzaska, W.H., Sillanpaa, M., Smirnov, S., Tiourin, G., Hagino, K., Rowley, N.   +25 more
openaire   +3 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

The clinical, serological and myopathological features of a cohort of Chinese patients with inclusion body myositis: a single center analysis. [PDF]

Front Immunol
Qiu H, Yang S, Guo X, Leng Y, Zhao Y, Yu M, Zheng Y, Meng L, Lv H, Deng J, Zhang W, Wang Z, Yuan Y, Gang Q.   +13 more
europepmc   +1 more source

Weak*-weak* continuous derivations

International Mathematical Forum, 2007
D. Ebrahimi Bagha, S. A. R. Hoseinioun
openaire   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Hypokalemia-Induced Rhabdomyolysis Following Prolonged Diarrhea in a Child With Congenital Heart Disease Receiving Loop Diuretics: A Case Report and Literature Review. [PDF]

Cureus
Iwasaki K, Akiyoshi M, Nakashima S, Yasuda K, Taketani T.   +4 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source