Results 151 to 160 of about 400,831 (317)
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Department of Energy: Need to Address Longstanding Management Weaknesses [PDF]
, 1999 Testimony issued by the General Accounting Office with an abstract that begins "Pursuant to a congressional request, GAO discussed proposals for reorganizing the Department of Energy (DOE), focusing on: (1) longstanding weaknesses in DOE's management ...
United States. General Accounting Office.
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The relationship marketing in the process of customer loyalty. Case large construction of Manizales
Inquietud Empresarial, 2015 This paper is based on the model Lindgreen (2001), upholding the relationship marketing should be approached in three dimensions: objectives, definition of constructs and tools, which enable better customer management within organizations.
María Cristina Torres Camacho +1 more
doaj
SWOT analysis of the international freight road transport sector of Ukraine
Фінансово-кредитні системи: перспективи розвитку.In ensuring the free movement of goods between Ukraine and its external partners, in particular the EU, the sphere of international freight road transportations of Ukraine plays an important role. Problem statement.
Olesia Totska, Maksym Prosvirnikov
doaj +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Weaknesses and Solutions of Students in Writing Descriptive Text [PDF]
, 2019 This research focused on the students’ writing descriptive text and strategies in teaching writing descriptive text. The objective of this research was to find out the weaknesses of students’ descriptive writing text and the strategies used in overcoming
Hajar, Sitti
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FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Information Security: Weaknesses at 22 Agencies [PDF]
, 1999 Correspondence issued by the General Accounting Office with an abstract that begins "Pursuant to a congressional request, GAO reviewed computer security weaknesses within 22 federal agencies' operations.
United States. General Accounting Office.
core
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source