Results 41 to 50 of about 163,433 (313)

3D characterisation of tool wear whilst diamond turning silicon [PDF]

, 2006
Nanometrically smooth infrared silicon optics can be manufactured by the diamond turning process. Due to its relatively low density, silicon is an ideal optical material for weight sensitive infrared (IR) applications. However, rapid diamond tool edge
Luo, X., Impey, Susan A., Jacklin, T., Durazo-Cardenas, Isidro, Cox, Andrew, Shore, Paul   +5 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Fe nano-particle coatings for high temperature wear resistance

, 2011
Oxidational wear continues to present an economic challenge for the replacement of components subject to high temperature fretting and sliding contacts in applications such as gas turbine engines.
S.R. Saranu, A.H. Kean, Wood, R.J.K., Robert Wood, Walker, J.C., John Christopher Walker, A. H. Kean, Saranu, S.R., J.C. Walker, S. R. Saranu, R. J. K. Wood, Kean, A.H., R.J.K. Wood   +12 more
core   +1 more source

Wear and Friction Modeling on Lifeboat Launch Systems [PDF]

, 2010
The RNLI provides search and rescue cover along the UK and RoI coast using a variety of lifeboats and launch techniques. In locations where there is no natural harbour it is necessary to use a slipway to launch the lifeboat into the sea.
M. Hadfield, Thomas, Ben, Hadfield, Mark, S. Austen, B. Thomas, Austen, S.   +5 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Is there evidence for accelerated polyethylene wear in uncemented compared to cemented acetabular components? A systematic review of the literature [PDF]

, 2013
Joint arthroplasty registries show an increased rate of aseptic loosening in uncemented acetabular components as compared to cemented acetabular components.
van Raay, J.J.A.M., van Jonbergen, H.P., van Jonbergen, H.P.W., Poolman, R.W., van der Veen, Hugo, van der Veen, H.C., van Raay, J.J., Bulstra, S.K.   +7 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Preparation of highly wear-resistant non-skid deck coating and analysis of its non-skid wear resistance

Zhongguo Jianchuan Yanjiu, 2020
[Objectives] In order to solve the wear problem of ship decks caused by major equipment, a new highly wear-resistant anti-skid deck coating is developed.[Methods] The coating is mainly composed of a primer,non-skid layer and topcoat.
DENG Qi, WANG Tongliang, BAI Yang, JIANG Xiujie   +3 more
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source