Results 51 to 60 of about 163,433 (313)

Usability testing of a digital tool to support behavioural activation for depression with young people aged 12 to 18

Frontiers in Child and Adolescent Psychiatry
BackgroundAdolescents with depression cannot access timely support due to pressures on specialist mental health services. We developed and tested a manualised version of behavioural activation—a brief psychological intervention—for delivery in the ...
Lucy Tindall, Philip Kerrigan, Emma Standley, Susan Metcalfe, Matthew O’Brien, Lina Gega   +5 more
doaj   +1 more source

Abrasive wear with particular reference to digger teeth [PDF]

, 1987
This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel University.Abrasive wear occurs when a contact associated with stress between a metal surface and a herd particle (frequently of mineral origin) leads to ...
Mashloosh, KM
core  

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Community-based behavioural activation for depression in adolescents: feasibility study, survey and stakeholder consultations

Frontiers in Child and Adolescent Psychiatry
BackgroundBehavioural activation, a brief psychological therapy for depression across the lifespan lends itself well for delivery in community settings (e.g., non-hospital health services, schools, charities).
Lucy Tindall, Emily Hayward, Jinshuo Li, Philip Kerrigan, Susan Metcalfe, Lina Gega, Lina Gega   +6 more
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Persistent Physical Symptoms—Healthcare Workers’ Experiences of Current Models of Care

Psychology International
Persistent physical symptoms (PPS) are frequently seen in most medical specialties. Healthcare provision for PPS patients has been largely ineffective due to an outdated biomedical approach and failure to encompass the multifaceted nature of PPS, despite
Lorelle Dismore, Stacie Thursby, Gail-Dovey Pearce, Iain Goff, Diarmaid Ferguson, David Tomson, Katherine Swainston   +6 more
doaj   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Impact of Wheel-rail Lubrication on Outer Rail Wear in Metro Small Radius Curved Segments

Chengshi guidao jiaotong yanjiu
[Objective] For metro lines with high proportion of small radius curved segments and severe rail wear, lubrication can alter wheel-rail contact area friction coefficient and in turn effectively reduce rail wear, thus it is necessary to study the ...
Xinwei LUO, Bin ZHANG, Longyang WANG, Qingsong FENG   +3 more
doaj   +1 more source

Wear Tests of a Potential Biolubricant for Orthopedic Biopolymers

, 2015
Most wear testing of orthopedic implant materials is undertaken with dilute bovine serum used as the lubricant. However, dilute bovine serum is different to the synovial fluid in which natural and artificial joints must operate. As part of a search for a
Thomas Joyce, Ben Hunt, Thompson, Martin, Hunt, Ben, Alan Smith, Smith, Alan M., Martin Thompson, Joyce, Thomas, Smith, Alan   +8 more
core   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source