Results 31 to 40 of about 70,132 (265)

Developing a work roll model by analyzing the mechanism influence through analytic calculation

International Journal of Applied Mechanics and Engineering, 2023
This paper presents a novel approach to developing a work roll prediction model that takes into account both the mechanism and condition influences on work roll wear.
Hussein Mohammed Ali Al Mohammed
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Comparative study of wear behavior of magnesium matrix composite reinforced with silicon carbide particles and whiskers before and after extrusion

Journal of Magnesium and Alloys
In the current study the wear behavior of the ZK60/SiC composites reinforced by particles and whiskers in both as-cast and extruded conditions was examined.
Morteza Tayebi, Ali Reza Eivani, Mosab Kaseem, Maryam Mehdizade, Hamid Reza Jafarian   +4 more
doaj   +1 more source

Microstructure and wear resistance of in-situ TiC reinforced Stellite 6 coating using PTA cladding

Journal of Materials Research and Technology, 2023
To enhance the durability of copper tuyeres in blast furnaces, it is necessary to apply coatings on their surfaces to protect against wear caused by high-temperature coke.
Ruidong Wang, Shuixin Ye, Peng Cheng, Zhengya Xie, Yi Wang, Yuwen Zhang, Guangshi Li, Wenhe Wu, Xionggang Lu   +8 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Preparation and tribological properties of WS2 solid lubricating coating with dense structure using HiPIMS

Journal of Materials Research and Technology
In this study, a dense WS2 coating was deposited via high-power impulse magnetron sputtering (HiPIMS) after solving the glow discharge problem, and it was compared with WS2 coating deposited via radio frequency (RF) sputtering.
Puyou Ying, Hanying Sun, Ping Zhang, Changhong Lin, Tao Yang, Jianbo Wu, Min Huang, Tianle Wang, Zhibiao Lian, Vladimir Levchenko   +9 more
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Wear resistance of steels under mechanical wear [PDF]

Metaloznavstvo ta obrobka metalìv, 2020
The potential possibilities of high-carbon low-alloy steels as a wear-resistant material under conditions of abrasive and other types of mechanical wear are considered. It is shown that the carbon content in steel at 1.2% mass. and up to 3% of alloying elements in total (mainly Mn, Cr), after quenching from the single-phase γ-region, allow obtaining up
openaire   +2 more sources

Profound Leadership Strategies: Transcending the Leadership Crisis in the Age of Artificial Intelligence

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley   +1 more source