Results 41 to 50 of about 69,107 (284)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Wearable Devices for Environmental Monitoring in the Built Environment: A Systematic Review
Sensors, 2021 The so-called Internet of Things (IoT), which is rapidly increasing the number of network-connected and interconnected objects, could have a far-reaching impact in identifying the link between human health, well-being, and environmental concerns. In line
Francesco Salamone +2 more
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Frontiers in Physiology, 2017 Background: In the past years, there was an increasing development of physical activity tracker (Wearables). For recreational people, testing of these devices under walking or light jogging conditions might be sufficient.
Yvonne Wahl +6 more
doaj +1 more source
National Science Review, 2022 This perspective article highlights the recent advances and future challenges of battery technologies for wearables.
Wang, L, Zhang, Y, Bruce, PG
openaire +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Nature CommunicationsCurrent conventions, partly derived from self-reported data, typically equate 1 minute of vigorous physical activity (VPA) to 2 minutes of moderate physical activity (MPA).
Raaj Kishore Biswas +5 more
doaj +1 more source
Cuff-Less Methods for Blood Pressure Telemonitoring. [PDF]
, 2019 Blood pressure telemonitoring (BPT) is a telemedicine strategy that uses a patient\u27s self-measured blood pressure (BP) and transmits this information to healthcare providers, typically over the internet.
Bard, Dylan M. +2 more
core +2 more sources
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
BMC Public HealthBackground Sleep is a crucial lifestyle factor with impacts on mental and cognitive health. The associations between objectively measured sleep and risk of incident dementia are not yet fully understood.
Wenxin Bian +10 more
doaj +1 more source