Results 51 to 60 of about 69,107 (284)
Ambulatory Tasks and Journeys: A Framework for Free-Living Behaviour
Background: Standard accelerometer summaries obscure meaningful differences in how people move while upright. We introduce an operational two-class Ambulatory Behaviour Framework that separates Ambulatory Tasks—periods of standing and short continuous ...
Craig Speirs +5 more
doaj +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Background Vigorous intermittent lifestyle physical activity (VILPA) completed through normal daily living may offer a time-efficient avenue to accrue physical activity in a behaviourally sustainable manner.
Nicholas A. Koemel +7 more
doaj +1 more source
Elderly diabetic patients in developed countries have been widely using digital health wearables for many years to manage their diabetes-related health data accurately.
Ashfaq Ahmad +3 more
doaj +1 more source
Fog Computing in Medical Internet-of-Things: Architecture, Implementation, and Applications
In the era when the market segment of Internet of Things (IoT) tops the chart in various business reports, it is apparently envisioned that the field of medicine expects to gain a large benefit from the explosion of wearables and internet-connected ...
Abtahi, Mohammadreza +9 more
core +1 more source
Wearable Wireless Devices [PDF]
With the growing interest in the use of technology in daily life, the potential of using wearable wireless devices across multiple segments, e [...]
Abbasi, Qammer H. +2 more
openaire +3 more sources
Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein +13 more
wiley +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Considerations for integrating wearables into the everyday healthcare practice
Wearable technologies are becoming ever more popular as suggested tools for use in modern medicine. Studies evidence their growing pragmatism and provision of objective data for a more informative and personalised approach to patient care.
Dylan Powell, Alan Godfrey
doaj +1 more source

