Results 51 to 60 of about 295,907 (267)

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera   +20 more
wiley   +1 more source

Evaluation of the impact of atmospheric pressure in different seasons on blood pressure in patients with arterial hypertension

open access: yesInternational Journal of Occupational Medicine and Environmental Health, 2016
Objectives: Atmospheric pressure is the most objective weather factor because regardless of if outdoors or indoors it affects all objects in the same way.
Marek Kamiński   +11 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez   +5 more
wiley   +1 more source

DYNAMICS OF NUMBER OF Metopolophium dirhodum (Walk.) (Hemiptera, Aphididae) OCCURRING ON SHRUBS OF ROSES IN LUBLIN

open access: yesActa Scientiarum Polonorum: Hortorum Cultus, 2006
The purpose of the studies was to observe the dynamics of number of Metopolophium dirhodum (Walk.) on rugosa rose, multiflowered rose, park rose cv. ‘Grandhotel’ and different varieties of border roses.
Katarzyna Kmieć
doaj  

The relationship between nasal fracture patients and weather conditions [PDF]

open access: yesJournal of Preventive and Complementary Medicine
Background: Isolated nasal bone fractures are among the most prevalent facial injuries. Although the relationship between weather conditions and nasal fractures has not been extensively studied, it is reasonable to hypothesize a correlation.Objectives ...
Yeşim Yüksel   +5 more
doaj   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Employment Trajectories of Patients With Systemic Lupus Erythematosus and Factors Driving Transitions Between States

open access: yesArthritis Care &Research, EarlyView.
Objective Systemic lupus erythematosus (SLE) significantly impacts employment capacity. This study aimed to investigate the impact of burden of disease activity, damage, and treatment on employment outcomes and transitions in patients with SLE. Methods Using data from a single center, we analyzed employment transitions, adjusted mean disease activity ...
Javier Mencia‐Ledo   +4 more
wiley   +1 more source

Correlations of Genotype with Climate Parameters Suggest Caenorhabditis elegans Niche Adaptations

open access: yesG3: Genes, Genomes, Genetics, 2017
Species inhabit a variety of environmental niches, and the adaptation to a particular niche is often controlled by genetic factors, including gene-by-environment interactions.
Kathryn S. Evans   +5 more
doaj   +1 more source

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