Results 81 to 90 of about 263,417 (324)
A PANoptosis‐Based Signature for Survival and Immune Predication in Glioblastoma Multiforme
ABSTRACT Objective PANoptosis is a concept of total cell death characterized by pyroptosis, apoptosis, and necroptosis. We aimed to explore the clinical significance of PANoptosis‐related genes (PARGs) in glioblastoma multiforme (GBM). Methods Expression profiles of GBM were downloaded from the XENA database as a training dataset to construct a ...
Jun Yang+4 more
wiley +1 more source
Describe las formas de monitoreo web existentes, poniendo el foco en como estas herramientas gestionan la privacidad de los datos, con el objetivo de brindar recomendaciones en cuanto a la adopción de software de analítica web en las unidades de ...
Ramiro Federico Uviña
doaj
ABSTRACT Objectives To investigate whether pulse pressure or mean arterial pressure mediates the relationship between age and white matter hyperintensity load and to examine the mediating effect of white matter hyperintensities on cognition. Methods Demographic information, blood pressure, current medication lists, and Montreal Cognitive Assessment ...
Jade Hannan+8 more
wiley +1 more source
WEB SERVICES FOR BIG EARTH OBSERVATION DATA
The aim of geospatial web services is to enable users to share and process geospatial data on the Web, no matter what platform or protocol is used. In this paper, we investigate what the design decisions needed to implement web services for big Earth ...
Lubia Vinhas+3 more
doaj
Web-analytics for Increase of Efficiency of the Web-site of a Department of a Higher Educational Establishment Веб-аналитика для повышения эффективности сайта кафедры высшего учебного заведения [PDF]
The goal of the article lies in the study of efficiency of the web-site of the Department of Mathematical Modelling of Economic Systems of the National Technical University of Ukraine “Kyiv Polytechnic Institute” (mses.kpi.ua) using the data obtained ...
Tsesliv Olga V.
doaj
On web-applications usability testing
The paper discusses the task of organizing the usability testing of web applications that are in pilot or industrial operation. A usability testing technique is described that combines the development, debugging and execution of test scenarios, and ...
Boris M. Basok+2 more
doaj +1 more source
ABSTRACT Objective Despite the availability of effective therapies for Multiple Sclerosis (MS), the unpredictable nature of disease progression and the variability in individual treatment outcomes call for reliable biomarkers. This pilot study aims to investigate the potential of plasma circulating microRNAs (miRNAs) as predictive biomarkers for ...
Fortunata Carbone+19 more
wiley +1 more source
In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics
ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock+8 more
wiley +1 more source
ABSTRACT Objective Spinal muscular atrophy (SMA) significantly impacts motor function. This study aimed to assess the persistent burden and unmet needs among currently treated patients with SMA and their caregivers. Methods Two complementary web‐based surveys were distributed in August 2024 among patients with SMA and their caregivers.
Julie A. Parsons+8 more
wiley +1 more source